Pre_GI: BLASTP Hits

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Query: NC_004741:3240909:3260590 Shigella flexneri 2a str. 2457T, complete genome

Start: 3260590, End: 3261870, Length: 1281

Host Lineage: Shigella flexneri; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This is a highly virulent strain that has been widely used for genetic and clinical research. Causes enteric disease. This genus is named for the Japanese scientist (Shiga) who discovered them in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, and over 1 million deaths worldwide are attributed to them. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that require very few cells in order to cause disease. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism, along with Shigella sonnei, is the major cause of shigellosis in industrialized countries and is responsible for endemic infections.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017328:3289853:3309535330953533108151281Shigella flexneri 2002017 chromosome, complete genomeputative tagatose 6-phosphate kinase 20884
NC_004337:3249791:3269472326947232707521281Shigella flexneri 2a str. 301, complete genomeputative tagatose 6-phosphate kinase 20884
NC_012967:3191319:3211842321184232131221281Escherichia coli B str. REL606 chromosome, complete genometagatose 6-phosphate aldolase 1, kbaZ subunit0879
AC_000091:3258377:3278769327876932800491281Escherichia coli W3110 DNA, complete genometagatose 6-phosphate aldolase 1, kbaZ subunit0877
NC_000913:3256307:3276936327693632782161281Escherichia coli K12, complete genometagatose 6-phosphate aldolase 1, kbaZ subunit0877
NC_010473:3354052:3374681337468133759611281Escherichia coli str. K-12 substr. DH10B, complete genometagatose 6-phosphate aldolase 1, kbaZ subunit0877
NC_012759:3143455:3164084316408431653641281Escherichia coli BW2952 chromosome, complete genometagatose 6-phosphate aldolase 1, kbaZ subunit0877
CP002185:3475991:3496618349661834978981281Escherichia coli W, complete genometagatose 6-phosphate aldolase 1, KbaZ subunit0875
NC_011750:3768692:3791758379175837930381281Escherichia coli IAI39 chromosome, complete genometagatose 6-phosphate aldolase 1, kbaZ subunit0874
NC_011751:3710786:3733854373385437351341281Escherichia coli UMN026 chromosome, complete genometagatose 6-phosphate aldolase 1, kbaZ subunit0874
NC_013941:3884725:3907791390779139090711281Escherichia coli O55:H7 str. CB9615 chromosome, complete genomeD-tagatose-bisphosphate aldolase, class II, non-catalytic subunit0872
NC_006155:3596120:3630317363031736316151299Yersinia pseudotuberculosis IP 32953, complete genomeputative tagatose 6-phosphate kinase5e-149527
NC_010634:3509880:3544077354407735453751299Yersinia pseudotuberculosis PB1/+, complete genomeD-tagatose-bisphosphate aldolase, class II, non-catalytic subunit7e-149527
NC_015957:7533000:7547088754708875483831296Streptomyces violaceusniger Tu 4113 chromosome, complete genomeD-tagatose-bisphosphate aldolase, class II, non-catalytic subunit2e-140499
NC_012962:869295:8796548796548809611308Photorhabdus asymbiotica, complete genomeputative tagatose 6-phosphate kinase 21e-132473
NC_016818:3736213:3749649374964937509441296Rahnella aquatilis CIP 78.65 = ATCC 33071 chromosome, completeD-tagatose-bisphosphate aldolase non-catalytic subunit6e-122437
NC_017047:3793000:3806846380684638081411296Rahnella aquatilis HX2 chromosome, complete genomeD-tagatose-1,6-bisphosphate aldolase subunit GatZ1e-121437
NC_015061:3725921:3742200374220037434951296Rahnella sp. Y9602 chromosome, complete genomeD-tagatose-bisphosphate aldolase, class II, non-catalytic subunit1e-121437
NC_010338:359940:3586493586493599471299Caulobacter sp. K31, complete genomeD-tagatose-bisphosphate aldolase, class II, non-catalytic subunit1e-120433
NC_004431:2444972:2465101246510124663631263Escherichia coli CFT073, complete genomePutative tagatose 6-phosphate kinase gatZ2e-118426
NC_008253:2198583:2215636221563622168981263Escherichia coli 536, complete genomeputative tagatose 6-phosphate kinase gatZ1e-118426
NC_012483:971592:9914009914009926651266Acidobacterium capsulatum ATCC 51196, complete genomeD-tagatose-bisphosphate aldolase, class II, non-catalytic subunit1e-115417
NC_011898:1218500:1253224125322412545401317Clostridium cellulolyticum H10, complete genomeD-tagatose-bisphosphate aldolase class II accessory protein AgaZ3e-107388
NC_013165:1665014:1668732166873216700661335Slackia heliotrinireducens DSM 20476, complete genomepredicted tagatose 6-phosphate kinase1e-94347
NC_014364:1116439:1152379115237911537101332Spirochaeta smaragdinae DSM 11293 chromosome, complete genomeD-tagatose-bisphosphate aldolase class II accessory protein AgaZ9e-74277
NC_004431:1119700:113994111399411140564624Escherichia coli CFT073, complete genomehypothetical protein7e-49195
NC_007946:1073135:109335810933581093981624Escherichia coli UTI89, complete genomehypothetical protein7e-49195