Pre_GI: BLASTP Hits

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Query: NC_004668:2938000:2957485 Enterococcus faecalis V583, complete genome

Start: 2957485, End: 2958438, Length: 954

Host Lineage: Enterococcus faecalis; Enterococcus; Enterococcaceae; Lactobacillales; Firmicutes; Bacteria

General Information: This strain is one of the first vancomycin-resistant strains isolated. This isolate came from a blood culture derived from a chronically-infected patient in 1987 from Barnes Hospital in St. Louis, Missouri, USA. This strain was found to lack the cytolysin gene and a surface adhesin, Esp, that contributes to urinary tract infections. Mobile genetic elements make up one quarter of the genome. This genera consists of organisms typically found in the intestines of mammals, although through fecal contamination they can appear in sewage, soil, and water. They cause a number of infections that are becoming increasingly a problem due to the number of antibiotic resistance mechanisms these organisms have picked up. Both Enterococcus faecalis and Enterococcus faecium cause similar diseases in humans, and are mainly distinguished by their metabolic capabilities. This opportunistic pathogen can cause urinary tract infections, bacteremia (bacteria in the blood), and infective endocarditis (inflammation of the membrane surrounding the heart), similar to infections caused by Enterococcus faecium. Hospital-acquired infections from this organism are on the rise due to the emergence of antiobiotic resistance strains. Enterococcus faecalis produces a cytolysin toxin that is encoded on various mobile genetic elements, pathogenicity islands, and conjugative plasmids. The cytolysin aids in pathogenesis, possibly by causing destruction of cells such as erythrocytes, which allows access to new nutrients for the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017316:2466244:248510924851092486062954Enterococcus faecalis OG1RF chromosome, complete genomeferric (Fe+3) ABC superfamily ATP binding cassette transporter, binding protein1e-168592
NC_014829:405104:4260594260594270601002Bacillus cellulosilyticus DSM 2522 chromosome, complete genomeperiplasmic binding protein3e-61235
NC_004193:375416:375416375416675301299886Oceanobacillus iheyensis HTE831, complete genome1e-49197
NC_012846:1837924:185235218523521853302951Bartonella grahamii as4aup, complete genomeferric anguibactin-binding protein1e-48193
NC_015436:1287873:129237712923771293339963Spirochaeta coccoides DSM 17374 chromosome, complete genomeperiplasmic binding protein3e-48192
NC_010465:62348:795577955780510954Yersinia pseudotuberculosis YPIII, complete genomeperiplasmic binding protein9e-48191
NC_017160:4508000:451075445107544511707954Yersinia pestis D182038 chromosome, complete genomeputative iron transport protein9e-48191
NC_010161:1914000:192907519290751930025951Bartonella tribocorum CIP 105476, complete genomeferric anguibactin-binding protein6e-48191
NC_004193:375416:5751775751775762051029Oceanobacillus iheyensis HTE831, complete genomeferrichrome ABC transporter binding protein5e-48191
NC_005955:1205836:122006012200601220959900Bartonella quintana str. Toulouse, complete genomeFerric anguibactin-binding protein1e-47190
NC_020418:1397112:142402214240221424978957Morganella morganii subsp. morganii KT, complete genomeFerric anguibactin-binding protein2e-45182
NC_014532:2108897:213387521338752134855981Halomonas elongata DSM 2581, complete genomeABC-type transport system periplasmic substrate-binding protein4e-43175
NC_016816:1137904:113790411379041138848945Pantoea ananatis LMG 5342, complete genomeiron siderophore (ferrichrome) ABC transporter substrate-binding protein2e-40166
NC_013956:3273340:329930032993003300244945Pantoea ananatis LMG 20103 chromosome, complete genomeFatB3e-40166
NC_010120:199942:221885221885222850966Neisseria meningitidis 053442, complete genomeiron(III) ABC transporter, periplasmic binding protein9e-40164
NC_019897:763412:7839967839967850661071Thermobacillus composti KWC4 chromosome, complete genomeenterochelin ABC transporter substrate-binding protein4e-1995.5
NC_010184:4879552:4880588488058848816011014Bacillus weihenstephanensis KBAB4, complete genomeperiplasmic binding protein4e-1892.4
NC_006510:2910000:292648229264822927423942Geobacillus kaustophilus HTA426, complete genomeferrichrome ABC transporter (substrate-binding protein)1e-1480.9
NC_014915:3039639:304614030461403047081942Geobacillus sp. Y412MC52 chromosome, complete genomeperiplasmic binding protein1e-1480.5
NC_000911:15937:167401674017687948Synechocystis sp. PCC 6803, complete genomeiron(III) dicitrate transport system permease protein; FecB2e-1273.2
NC_017039:15937:167401674017687948Synechocystis sp. PCC 6803 substr. PCC-P, complete genomeiron(III) dicitrate transport system permeaseprotein2e-1273.2
NC_017052:15937:167401674017687948Synechocystis sp. PCC 6803 substr. PCC-N, complete genomeiron(III) dicitrate transport system permeaseprotein2e-1273.2
NC_017277:15937:167401674017687948Synechocystis sp. PCC 6803, complete genomeiron(III) dicitrate transport system permeaseprotein2e-1273.2
NC_003450:3266604:3284397328439732854251029Corynebacterium glutamicum ATCC 13032, complete genomeABC-type transport systems, periplasmic component4e-1272.4
NC_006958:3240019:3257704325770432587321029Corynebacterium glutamicum ATCC 13032, complete genomeABC-type cobalamin/Fe3+-siderophores transport system, secreted component4e-1272.4
NC_003366:981105:994044994044994988945Clostridium perfringens str. 13, complete genomeprobable iron(III) dicitrate ABC transporter6e-1168.6
NC_019897:3669888:3669888366988836709221035Thermobacillus composti KWC4 chromosome, complete genomeFe3+-hydroxamate ABC transporter substrate-binding protein3e-1066.2
NC_014507:611625:6369756369756380451071Methanoplanus petrolearius DSM 11571 chromosome, complete genomeperiplasmic binding protein3e-1065.9
NC_008262:904000:920802920802921746945Clostridium perfringens SM101, complete genomePeriplasmic binding protein family2e-0963.5
NC_001263:2574755:2595145259514525961521008Deinococcus radiodurans R1 chromosome 1, complete sequenceiron ABC transporter, periplasmic substrate-binding protein, putative3e-0962.8
NC_017200:4240500:424055542405554241499945Bacillus thuringiensis serovar finitimus YBT-020 chromosome,iron compound ABC transporter substrate-binding protein4e-0962.4
NC_014622:3955851:3980635398063539816751041Paenibacillus polymyxa SC2 chromosome, complete genomeiron(III) dicitrate ABC transporter permease8e-0961.2
NC_016612:3843358:386816338681633869065903Klebsiella oxytoca KCTC 1686 chromosome, complete genomeiron-dicitrate transporter substrate-binding subunit1e-0861.2
NC_008553:1717000:1724924172492417260421119Methanosaeta thermophila PT, complete genomeperiplasmic binding protein1e-0860.8
NC_008553:1717000:1727250172725017282691020Methanosaeta thermophila PT, complete genomeperiplasmic binding protein5e-0858.9
NC_006371:1973500:198304319830431983993951Photobacterium profundum SS9 chromosome 2, complete sequencehypothetical protein2e-0757
NC_016513:1761830:1763372176337217644181047Aggregatibacter actinomycetemcomitans ANH9381 chromosome, completeiron chelation ABC transporter periplasmic-binding protein3e-0756.2
NC_013416:1429881:1434921143492114359671047Aggregatibacter actinomycetemcomitans D11S-1, complete genomeiron chelatin ABC transporter periplasmic-binding protein3e-0756.2
NC_020410:3755978:375597837559783756940963Bacillus amyloliquefaciens subsp. plantarum UCMB5036 completeABC transporter (ferrioxamine binding lipoprotein)7e-0755.1
NC_013385:1617338:1629574162957416310251452Ammonifex degensii KC4, complete genomecopper amine oxidase domain protein8e-0754.7
NC_015573:2187688:2205510220551022065471038Desulfotomaculum kuznetsovii DSM 6115 chromosome, complete genomeABC transporter periplasmic protein1e-0654.3
NC_014228:3591758:360334936033493604248900Xenorhabdus nematophila ATCC 19061, complete genomeIron(III) dicitrate-binding periplasmic protein precursor FecB1e-0654.3
NC_014831:1557485:1558876155887615599131038Thermaerobacter marianensis DSM 12885 chromosome, complete genomeperiplasmic binding protein2e-0653.5
NC_016641:2618587:264155326415532642545993Paenibacillus terrae HPL-003 chromosome, complete genomesiderophore iron ABC transporter substrate-binding protein3e-0653.1
NC_013741:838243:8518538518538529231071Archaeoglobus profundus DSM 5631, complete genomeperiplasmic binding protein4e-0652.8
NC_016932:1041306:105460710546071055512906Corynebacterium pseudotuberculosis 316 chromosome, complete genomeIron ABC transporter substrate-binding protein6e-0652
NC_014329:1041556:106299110629911063896906Corynebacterium pseudotuberculosis FRC41 chromosome, completeiron ABC transporter substrate-binding protein6e-0652
NC_017300:1045555:106046410604641061369906Corynebacterium pseudotuberculosis 1002 chromosome, completeIron ABC transporter substrate-binding protein6e-0652
NC_017031:1039548:106281410628141063719906Corynebacterium pseudotuberculosis P54B96 chromosome, completeIron ABC transporter substrate-binding protein6e-0652
NC_017301:1037519:106262710626271063532906Corynebacterium pseudotuberculosis C231 chromosome, completeIron ABC transporter substrate-binding protein6e-0652
NC_017303:1039562:106282810628281063733906Corynebacterium pseudotuberculosis I19 chromosome, complete genomeIron ABC transporter substrate-binding protein6e-0652
NC_017305:1037133:106039910603991061304906Corynebacterium pseudotuberculosis PAT10 chromosome, completeIron ABC transporter substrate-binding protein6e-0652
NC_014507:611625:6315546315546328191266Methanoplanus petrolearius DSM 11571 chromosome, complete genomeperiplasmic binding protein5e-0652
NC_005957:4311679:432630743263074327281975Bacillus thuringiensis serovar konkukian str. 97-27, completeiron compound ABC transporter, iron compound-binding protein9e-0651.2
NC_016781:1039716:106304810630481063887840Corynebacterium pseudotuberculosis 3/99-5 chromosome, completeiron ABC transporter substrate-binding protein9e-0651.2
NC_012962:4591295:460186646018664602774909Photorhabdus asymbiotica, complete genomeiron(iii) dicitrate-binding periplasmic protein fecb1e-0551.2