Pre_GI: BLASTP Hits

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Query: NC_003155:4592000:4620386 Streptomyces avermitilis MA-4680, complete genome

Start: 4620386, End: 4620742, Length: 357

Host Lineage: Streptomyces avermitilis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (ATCC 31267) was isolated and characterized in 1978 by R. Burg and colleagues from a soil sample collected in Shizuoka Prefecture, Japan. Antibiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This organism is a well known producer of the anti-parasitic agent avermectin which is widely used to rid livestock of worm and insect infestations and to protect large numbers of people from river blindness in sub-Saharan Africa.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_003155:4906639:491244549124454912801357Streptomyces avermitilis MA-4680, complete genomereplication activator protein Pra3e-48190
NC_013929:5248000:526216752621675262523357Streptomyces scabiei 87.22 chromosome, complete genomereplication activator protein6e-48189
NC_013929:3299736:334298833429883343335348Streptomyces scabiei 87.22 chromosome, complete genomeregulatory protein5e-30129
NC_003888:3602753:360842036084203608776357Streptomyces coelicolor A3(2), complete genomeregulatory protein2e-29127
NC_016114:3575955:358270335827033583065363Streptomyces flavogriseus ATCC 33331 chromosome, complete genomeregulatory protein6e-27119
NC_003888:5790104:581081058108105811163354Streptomyces coelicolor A3(2), complete genomeregulatory protein2e-25114
NC_018750:4333064:433945243394524339784333Streptomyces venezuelae ATCC 10712, complete genomeputative replication activator protein Pra4e-23106
NC_010572:3925803:393532939353293935661333Streptomyces griseus subsp. griseus NBRC 13350, complete genomeputative replication activator protein Pra3e-22103
NC_021177:3997727:401169340116934012037345Streptomyces fulvissimus DSM 40593, complete genomeReplication activator protein pra6e-22102
NC_016582:7101701:711058271105827110914333Streptomyces bingchenggensis BCW-1 chromosome, complete genomereplication activator protein Pra2e-1891.3
NC_016109:4581467:459137845913784591767390Kitasatospora setae KM-6054, complete genomeputative regulatory protein2e-1684
NC_015953:1860946:186492318649231865231309Streptomyces sp. SirexAA-E chromosome, complete genome6e-1682.8
NC_013510:5115500:513536151353615135750390Thermomonospora curvata DSM 43183, complete genomehypothetical protein9e-1165.5
NC_014210:723719:734254734254734586333Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,hypothetical protein2e-0961.2
NC_016582:5393568:540606854060685406421354Streptomyces bingchenggensis BCW-1 chromosome, complete genomeregulatory protein3e-0650.4