Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:7101701 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
71017017102537837morphological differentiation-associated proteinQuickGO ontologyBLASTP
710300671041181113septum site determining proteinQuickGO ontologyBLASTP
71041157104738624putative Type IIIV secretory proteinQuickGO ontologyBLASTP
710477171064171647recombinaseQuickGO ontologyBLASTP
710662471081051482hypothetical proteinBLASTP
71082437108956714hypothetical proteinBLASTP
710900371103611359putative plasmid transfer proteinQuickGO ontologyBLASTP
71103887110585198hypothetical proteinBLASTP
71105827110914333replication activator protein PraQuickGO ontologyBLASTP
71110637111593531GntR family transcriptional regulator proteinQuickGO ontologyBLASTP
71128467113196351hypothetical protein
711330971145141206XRE family transcriptional regulatorQuickGO ontologyBLASTP
71146337115118486NUDIX hydrolaseQuickGO ontologyBLASTP
71152047115551348mannose-6-phosphate isomeraseQuickGO ontologyBLASTP
71158247116303480secretory proteinQuickGO ontologyBLASTP
71163217117232912putative type II secretion system F proteinQuickGO ontologyBLASTP
71172227118028807hypothetical proteinBLASTP
71181787118375198hypothetical proteinBLASTP
71184137118814402hypothetical proteinBLASTP
71188477119185339hypothetical protein
711947371218452373putative ATP-dependent RNA helicaseQuickGO ontologyBLASTP