Pre_GI Gene

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Host: NC_003888 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_003888:5790104 Streptomyces coelicolor A3(2), complete genome

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Well-studied antiobiotic-producing bacterium. These bacteria are widely distributed in nature, especially in the soil. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
579010457912971194whiE protein IQuickGO ontology
579164157935241884polyketide hydroxylaseQuickGO ontologyBLASTP
57936015794470870hypothetical proteinBLASTP
57945285795022495Asn-C family transcriptional regulatorQuickGO ontologyBLASTP
57951575795837681oxidoreductaseQuickGO ontologyBLASTP
57960535796373321hypothetical protein
57963245796578255hypothetical proteinBLASTP
57967365797479744transposaseQuickGO ontologyBLASTP
579877358004701698hypothetical proteinBLASTP
58009335801835903hypothetical proteinBLASTP
580199858056003603DNA methylaseQuickGO ontologyBLASTP
580582358073341512hypothetical proteinBLASTP
58074205808325906hypothetical proteinBLASTP
58088445809158315hypothetical protein
58091715809434264hypothetical proteinBLASTP
58094225809892471mutT-like proteinQuickGO ontologyBLASTP
58099215810652732hypothetical proteinBLASTP
58108105811163354regulatory proteinQuickGO ontologyBLASTP
581116758125221356plasmid transfer proteinQuickGO ontologyBLASTP
58125435812740198hypothetical protein
58127625813430669SpdA2 proteinQuickGO ontologyBLASTP
58134525813643192SpdB2 proteinQuickGO ontologyBLASTP
58136545813809156SpdC2 proteinQuickGO ontologyBLASTP
58138225814145324SpdD2 proteinQuickGO ontology
58142355814786552hypothetical proteinBLASTP
58148725815057186hypothetical protein
581505058164141365replication initiation proteinQuickGO ontologyBLASTP
58164165816601186excisionaseQuickGO ontologyBLASTP
581659858179711374integraseQuickGO ontologyBLASTP
58180035818548546hypothetical protein
5818721581879575tRNA-ArgQuickGO ontology
58189755819478504regulatory proteinQuickGO ontologyBLASTP
581960058206431044arginyl tRNA synthetaseQuickGO ontologyBLASTP