Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:5393568 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
53935685394539972ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
539466653958651200threonine dehydrataseQuickGO ontologyBLASTP
53960695396569501MarR family transcriptional regulatorQuickGO ontologyBLASTP
53966765397191516putative DNA-binding proteinQuickGO ontologyBLASTP
53972765397527252hypothetical protein
539754753987401194cystathionine gamma-synthaseQuickGO ontologyBLASTP
539886253999591098hypothetical proteinBLASTP
54000985400784687Peptide-methionine S-S-oxide reductaseQuickGO ontologyBLASTP
54010445401271228hypothetical proteinBLASTP
54013435401906564hypothetical proteinBLASTP
540204054032241185putative DNA-binding proteinQuickGO ontologyBLASTP
54035445403675132hypothetical protein
54036725403923252hypothetical proteinBLASTP
54039235404051129hypothetical protein
54044185404708291hypothetical proteinBLASTP
54051415405914774GntR family transcriptional regulatorQuickGO ontologyBLASTP
54060685406421354regulatory proteinQuickGO ontologyBLASTP
540642154077341314FtsKSpoIIIE family proteinQuickGO ontologyBLASTP
54077585407928171hypothetical proteinBLASTP
540820054096181419plasmid replication initiator proteinQuickGO ontologyBLASTP
540975654111441389recombinaseQuickGO ontologyBLASTP
54113905411770381HxlR family transcriptional regulatorQuickGO ontologyBLASTP
54118605412789930alcohol dehydrogenase GroES domain-containing proteinQuickGO ontologyBLASTP
54127865412893108hypothetical protein
54130535413577525hypothetical protein
54137485414110363hypothetical proteinBLASTP
54141205414881762hypothetical proteinBLASTP
54149355415564630hypothetical proteinBLASTP
54155125415991480hypothetical proteinBLASTP
54160445416523480hypothetical proteinBLASTP
541650454190712568hypothetical proteinBLASTP