Pre_GI Island

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n1_4mer:GRV/n1_4mer:RV = (Global Relative Variance of OU patterns) / (Local Relative Variance of OU patterns)

n0_4mer:D = Distance between local and global OU patterns

n0_4mer:PS = Distance between 2 strands of same DNA molecule

Selected loci indicated by large D, increased GRV associated with decreased RV and moderate increase in PS

NC_017215: Bifidobacterium animalis subsp. lactis CNCM I-2494 chromosome,

NCBI: NC_017215

Host Lineage: Bifidobacterium animalis; Bifidobacterium; Bifidobacteriaceae; Bifidobacteriales; Actinobacteria; Bacteria

General Information: Representatives of this genus naturally colonize the human gastrointestinal tract (GIT) and are important for establishing and maintaining homeostasis of the intestinal ecosystem to allow for normal digestion. Their presence has been associated with beneficial health effects, such as prevention of diarrhea, amelioration of lactose intolerance, or immunomodulation. The stabilizing effect on GIT microflora is attributed to the capacity of bifidobacteria to produce bacteriocins, which are bacteriostatic agents with a broad spectrum of action, and to their pH-reducing activity. Most of the ~30 known species of bifidobacteria have been isolated from the mammalian GIT, and some from the vaginal and oral cavity. All are obligate anaerobes belonging to the Actinomycetales, branch of Gram-positive bacteria with high GC content that also includes Corynebacteria, Mycobacteria, and Streptomycetes. Bifidobacterium animalis and Bifidobacterium lactis were originally considered to be separate species. Recent studies evaluating the DNA relatedness and phenotypic similarities of these species has determined that they represent a single species.

Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

#StartEndLengthIsland TextGRV_RVDPSNeighboursClusterSub ClusterBLASTNKey Word ConfirmationOther DB ConfirmationDownload Island
1226165368131066Island text2.3975835.442941.0994Neighbours116BLASTN+22616.gbk
266935869317123814Island text1.6379928.741124.4102Neighbours11BLASTN669358.gbk
31091941*111527123331Island text1.6317328.906222.8737Neighbours11BLASTN+1091941.gbk
41361822138524023419Island text1.5486226.541243.5449Neighbours11BLASTN+1361822.gbk
51499179152984130663Island text1.7360926.495638.0152Neighbours11BLASTN+1499179.gbk
61605917166290056984Island text2.0094335.37535.3097Neighbours116BLASTN+1605917.gbk
71687161171972132561Island text2.2694733.073628.0061Neighbours11BLASTN+1687161.gbk