Pre_GI Gene

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Host: NC_017215 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017215:1499179 Bifidobacterium animalis subsp. lactis CNCM I-2494 chromosome,

Host Lineage: Bifidobacterium animalis; Bifidobacterium; Bifidobacteriaceae; Bifidobacteriales; Actinobacteria; Bacteria

General Information: Representatives of this genus naturally colonize the human gastrointestinal tract (GIT) and are important for establishing and maintaining homeostasis of the intestinal ecosystem to allow for normal digestion. Their presence has been associated with beneficial health effects, such as prevention of diarrhea, amelioration of lactose intolerance, or immunomodulation. The stabilizing effect on GIT microflora is attributed to the capacity of bifidobacteria to produce bacteriocins, which are bacteriostatic agents with a broad spectrum of action, and to their pH-reducing activity. Most of the ~30 known species of bifidobacteria have been isolated from the mammalian GIT, and some from the vaginal and oral cavity. All are obligate anaerobes belonging to the Actinomycetales, branch of Gram-positive bacteria with high GC content that also includes Corynebacteria, Mycobacteria, and Streptomycetes. Bifidobacterium animalis and Bifidobacterium lactis were originally considered to be separate species. Recent studies evaluating the DNA relatedness and phenotypic similarities of these species has determined that they represent a single species.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
149917915012572079Multidrugproteinlipid ABC transporter family ATP-binding and permease proteinQuickGO ontologyBLASTP
150125415032271974Multidrug resistance ABC transporter ATP-binding and permease proteinQuickGO ontologyBLASTP
15032241503829606MarR family transcriptional regulatorQuickGO ontologyBLASTP
1503893150399199hypothetical proteinBLASTP
15040331504599567Oxidoreductase acting on the CH-OH group of donors with NAD or NADP as acceptorQuickGO ontologyBLASTP
15047131505225513Hydrolase acting on ester bondsQuickGO ontologyBLASTP
15054081505815408hypothetical protein
15061691506366198hypothetical proteinBLASTP
15063691506638270hypothetical proteinBLASTP
15067711507079309cytosolic proteinQuickGO ontologyBLASTP
150713815081841047cytosolic proteinQuickGO ontologyBLASTP
150818815112803093ATP-dependent helicaseQuickGO ontologyBLASTP
151123215128691638hypothetical proteinBLASTP
151288815141951308membrane associated proteinQuickGO ontologyBLASTP
15142111514531321hypothetical proteinBLASTP
151480315164341632hypothetical proteinBLASTP
15164971516979483cytosolic proteinQuickGO ontologyBLASTP
15171041517478375cytosolic proteinQuickGO ontologyBLASTP
151804715193181272glutamate--cysteine ligaseQuickGO ontologyBLASTP
151939215241524761Activator of R-2-hydroxyglutaryl-CoA dehydrataseQuickGO ontologyBLASTP
15243121524929618membrane spanning proteinQuickGO ontologyBLASTP
15249261525327402membrane spanning proteinQuickGO ontologyBLASTP
15253801526279900membrane associated proteinQuickGO ontologyBLASTP
15262761527025750Formate-C-acetyltransferase-activating enzymeQuickGO ontologyBLASTP
152736715298412475Ribonucleoside-triphosphate reductaseQuickGO ontologyBLASTP