Pre_GI Island

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n1_4mer:GRV/n1_4mer:RV = (Global Relative Variance of OU patterns) / (Local Relative Variance of OU patterns)

n0_4mer:D = Distance between local and global OU patterns

n0_4mer:PS = Distance between 2 strands of same DNA molecule

Selected loci indicated by large D, increased GRV associated with decreased RV and moderate increase in PS

NC_012578: Vibrio cholerae M66-2 chromosome I, complete sequence

NCBI: NC_012578

Host Lineage: Vibrio cholerae; Vibrio; Vibrionaceae; Vibrionales; Proteobacteria; Bacteria

General Information: Vibrio cholerae M66-2 was isolated from the 1937 cholera outbreak in the Makassar area of Indonesia. This genus is abundant in marine or freshwater environments such as estuaries, brackish ponds, or coastal areas; regions that provide an important reservoir for the organism in between outbreaks of the disease. Vibrio can affect shellfish, finfish, and other marine animals and a number of species are pathogenic for humans. Vibrio cholerae can colonize the mucosal surface of the small intestines of humans where it will cause cholera, a severe and sudden onset diarrheal disease. One famous outbreak was traced to a contaminated well in London in 1854 by John Snow, and epidemics, which can occur with extreme rapidity, are often associated with conditions of poor sanitation. The disease has a high lethality if left untreated, and millions have died over the centuries. There have been seven major pandemics between 1817 and today. Six were attributed to the classical biotype, while the 7th, which started in 1961, is associated with the El Tor biotype.

Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

#StartEndLengthIsland TextGRV_RVDPSNeighboursClusterSub ClusterBLASTNKey Word ConfirmationOther DB ConfirmationDownload Island
122455926138136823Island text1.5241234.712454.4067Neighbours21BLASTN+IslandViewer 224559.gbk
281824184735829118Island text1.530532.959947.7403Neighbours21BLASTN+IslandViewer 818241.gbk
393600095809922100Island text2.6102739.536123.6754Neighbours21BLASTN936000.gbk
41465302148436119060Island text1.6098734.994350.884Neighbours41BLASTN+IslandViewer 1465302.gbk
51838470*188586547396Island text1.5176330.4947.3444Neighbours41BLASTN+IslandViewer 1838470.gbk
62479150*250196522816Island text1.8024232.405225.0761Neighbours44BLASTN2479150.gbk