Pre_GI Gene

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Host: NC_012578 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012578:936000 Vibrio cholerae M66-2 chromosome I, complete sequence

Host Lineage: Vibrio cholerae; Vibrio; Vibrionaceae; Vibrionales; Proteobacteria; Bacteria

General Information: Vibrio cholerae M66-2 was isolated from the 1937 cholera outbreak in the Makassar area of Indonesia. This genus is abundant in marine or freshwater environments such as estuaries, brackish ponds, or coastal areas; regions that provide an important reservoir for the organism in between outbreaks of the disease. Vibrio can affect shellfish, finfish, and other marine animals and a number of species are pathogenic for humans. Vibrio cholerae can colonize the mucosal surface of the small intestines of humans where it will cause cholera, a severe and sudden onset diarrheal disease. One famous outbreak was traced to a contaminated well in London in 1854 by John Snow, and epidemics, which can occur with extreme rapidity, are often associated with conditions of poor sanitation. The disease has a high lethality if left untreated, and millions have died over the centuries. There have been seven major pandemics between 1817 and today. Six were attributed to the classical biotype, while the 7th, which started in 1961, is associated with the El Tor biotype.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
936059936559501phosphotyrosine protein phosphataseQuickGO ontologyBLASTP
9368729379901119UDP-N-acetylglucosamine 2-epimeraseQuickGO ontologyBLASTP
9380109392511242UDP-N-acetyl-D-mannosamine dehydrogenaseQuickGO ontologyBLASTP
939248939802555serine acetyltransferase-like proteinQuickGO ontologyBLASTP
9397999409471149putative exopolysaccharide biosynthesis proteinQuickGO ontologyBLASTP
9409449423531410putative polysaccharide export proteinQuickGO ontologyBLASTP
9423509435701221hypothetical proteinBLASTP
943581944012432serine acetyltransferase-like proteinQuickGO ontologyBLASTP
9440129453521341putative capK proteinQuickGO ontologyBLASTP
9453289464251098putative polysaccharide biosynthesis proteinQuickGO ontologyBLASTP
9464229475941173hypothetical proteinBLASTP
947584948336753UDP-N-acetyl-D-mannosamine transferaseQuickGO ontologyBLASTP
948532949347816hypothetical proteinBLASTP
9495539507791227hypothetical proteinBLASTP
9510439539162874hemolysin-like proteinQuickGO ontologyBLASTP
9540719553871317hypothetical proteinBLASTP
955563956168606hypothetical proteinBLASTP
9566589580551398putative capsular polysaccharide biosynthesis glycosyltransferaseQuickGO ontologyBLASTP