Pre_GI Gene

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Host: NC_012578 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012578:1838470 Vibrio cholerae M66-2 chromosome I, complete sequence

Host Lineage: Vibrio cholerae; Vibrio; Vibrionaceae; Vibrionales; Proteobacteria; Bacteria

General Information: Vibrio cholerae M66-2 was isolated from the 1937 cholera outbreak in the Makassar area of Indonesia. This genus is abundant in marine or freshwater environments such as estuaries, brackish ponds, or coastal areas; regions that provide an important reservoir for the organism in between outbreaks of the disease. Vibrio can affect shellfish, finfish, and other marine animals and a number of species are pathogenic for humans. Vibrio cholerae can colonize the mucosal surface of the small intestines of humans where it will cause cholera, a severe and sudden onset diarrheal disease. One famous outbreak was traced to a contaminated well in London in 1854 by John Snow, and epidemics, which can occur with extreme rapidity, are often associated with conditions of poor sanitation. The disease has a high lethality if left untreated, and millions have died over the centuries. There have been seven major pandemics between 1817 and today. Six were attributed to the classical biotype, while the 7th, which started in 1961, is associated with the El Tor biotype.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
183847018395641095putative periplasmic linker proteinQuickGO ontologyBLASTP
183956418426143051transporter AcrBDF familyQuickGO ontologyBLASTP
1842826184291388tRNA-SerQuickGO ontologyBLASTP
184322618444611236integrase phage familyQuickGO ontologyBLASTP
184514318485923450putative helicaseQuickGO ontologyBLASTP
184858318500341452hypothetical proteinBLASTP
18500311850765735chemotaxis protein MotB-like proteinQuickGO ontologyBLASTP
185075818528782121Restin-like proteinQuickGO ontologyBLASTP
185292318559913069putative type I restriction enzyme HsdRQuickGO ontologyBLASTP
185601918580101992hypothetical proteinBLASTP
185800318594151413hypothetical proteinBLASTP
185941618608041389hypothetical proteinBLASTP
186076118631422382putative DNA methylase HsdMQuickGO ontologyBLASTP
186328318653462064hypothetical proteinBLASTP
186532818689903663hypothetical proteinBLASTP
18690181869878861hypothetical proteinBLASTP
186994318710131071hypothetical proteinBLASTP
187102818721821155N-acetylneuraminic acid mutarotaseQuickGO ontologyBLASTP
18723641873200837Putative HTH-type transcriptional regulator ybbHQuickGO ontologyBLASTP
18733291874225897putative N-acetylneuraminate lyaseQuickGO ontologyBLASTP
187426318755461284Sialic acid TRAP transporterlarge permeaseQuickGO ontologyBLASTP
18755541876075522Sialic acid TRAP transporter small permeaseQuickGO ontologyBLASTP
18761261877091966C4-dicarboxylate-binding periplasmic proteinQuickGO ontologyBLASTP
18771221877415294hypothetical proteinBLASTP
18773061878028723N-acetylmannosamine-6-phosphate 2-epimeraseQuickGO ontologyBLASTP
18780161878879864N-acetylmannosamine kinaseQuickGO ontologyBLASTP
187888318800191137N-acetylglucosamine-6-phosphate deacetylaseQuickGO ontologyBLASTP
188036418827872424neuraminidaseQuickGO ontologyBLASTP
18829341883140207transcriptional regulatorQuickGO ontologyBLASTP
18832541883730477putative DNA repair protein RadCQuickGO ontologyBLASTP
18837271883864138hypothetical proteinBLASTP
18839601884655696hypothetical proteinBLASTP
18846521885524873ISVch4 transposase OrfBQuickGO ontologyBLASTP
18855211885865345ISVch4 transposase OrfAQuickGO ontologyBLASTP