Pre_GI Gene

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Host: NC_012578 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012578:1465302 Vibrio cholerae M66-2 chromosome I, complete sequence

Host Lineage: Vibrio cholerae; Vibrio; Vibrionaceae; Vibrionales; Proteobacteria; Bacteria

General Information: Vibrio cholerae M66-2 was isolated from the 1937 cholera outbreak in the Makassar area of Indonesia. This genus is abundant in marine or freshwater environments such as estuaries, brackish ponds, or coastal areas; regions that provide an important reservoir for the organism in between outbreaks of the disease. Vibrio can affect shellfish, finfish, and other marine animals and a number of species are pathogenic for humans. Vibrio cholerae can colonize the mucosal surface of the small intestines of humans where it will cause cholera, a severe and sudden onset diarrheal disease. One famous outbreak was traced to a contaminated well in London in 1854 by John Snow, and epidemics, which can occur with extreme rapidity, are often associated with conditions of poor sanitation. The disease has a high lethality if left untreated, and millions have died over the centuries. There have been seven major pandemics between 1817 and today. Six were attributed to the classical biotype, while the 7th, which started in 1961, is associated with the El Tor biotype.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
146530214668761575thermostable carboxypeptidase 1QuickGO ontologyBLASTP
14670741467592519hcp proteinQuickGO ontologyBLASTP
146772014712113492vgrG proteinQuickGO ontologyBLASTP
14711901472050861hypothetical proteinBLASTP
147205314739781926hypothetical proteinBLASTP
14739751474718744hypothetical proteinBLASTP
14748631475600738hypothetical proteinBLASTP
14756881476326639hypothetical proteinBLASTP
147639914777751377sodiumalanine symporterQuickGO ontologyBLASTP
14782781478436159hypothetical proteinBLASTP
14784531479187735hypothetical proteinBLASTP
147933414803711038spermidineputrescine ABC transporter substrate-binding proteinQuickGO ontologyBLASTP
148048314815831101spermidineputrescine ABC transporter substrate-binding proteinQuickGO ontologyBLASTP
14816171482387771spermidineputrescine ABC transporter membrane proteinQuickGO ontologyBLASTP
14823871483247861spermidineputrescine ABC transporter membrane proteinQuickGO ontologyBLASTP
148322814843611134putrescinespermidine ABC transporter ATPase proteinQuickGO ontologyBLASTP