Pre_GI Gene

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Host: NC_012578 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012578:2479150 Vibrio cholerae M66-2 chromosome I, complete sequence

Host Lineage: Vibrio cholerae; Vibrio; Vibrionaceae; Vibrionales; Proteobacteria; Bacteria

General Information: Vibrio cholerae M66-2 was isolated from the 1937 cholera outbreak in the Makassar area of Indonesia. This genus is abundant in marine or freshwater environments such as estuaries, brackish ponds, or coastal areas; regions that provide an important reservoir for the organism in between outbreaks of the disease. Vibrio can affect shellfish, finfish, and other marine animals and a number of species are pathogenic for humans. Vibrio cholerae can colonize the mucosal surface of the small intestines of humans where it will cause cholera, a severe and sudden onset diarrheal disease. One famous outbreak was traced to a contaminated well in London in 1854 by John Snow, and epidemics, which can occur with extreme rapidity, are often associated with conditions of poor sanitation. The disease has a high lethality if left untreated, and millions have died over the centuries. There have been seven major pandemics between 1817 and today. Six were attributed to the classical biotype, while the 7th, which started in 1961, is associated with the El Tor biotype.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
247915024805651416glutamate synthase subunit betaQuickGO ontologyBLASTP
24807522481186435hypothetical proteinBLASTP
248127424819696965-methylthioadenosineS-adenosylhomocysteine nucleosidaseQuickGO ontologyBLASTP
24819822482935954adenosylcobinamide-phosphate synthaseQuickGO ontologyBLASTP
24829362483766831Vitamin B12-binding proteinQuickGO ontologyBLASTP
24837502484469720hypothetical proteinBLASTP
24846212485481861LysR family transcriptional regulatorQuickGO ontologyBLASTP
24854112486196786putative Inner membrane proteinQuickGO ontologyBLASTP
24866582487629972RNA-directed DNA polymeraseQuickGO ontologyBLASTP
24892642489881618hypothetical proteinBLASTP
24904922490974483hypothetical proteinBLASTP
249106424942943231carbamoyl phosphate synthase large subunitQuickGO ontologyBLASTP
249431124954501140carbamoyl phosphate synthase small subunitQuickGO ontologyBLASTP
24959332496742810dihydrodipicolinate reductaseQuickGO ontologyBLASTP
24968572497255399mutator MutT proteinQuickGO ontologyBLASTP
24972412497408168hypothetical proteinBLASTP
249740525001162712preprotein translocase subunit SecAQuickGO ontologyBLASTP
25004702500943474hypothetical proteinBLASTP
25010482501965918UDP-3-O-3-hydroxymyristoyl N-acetylglucosamine deacetylaseQuickGO ontologyBLASTP