Pre_GI Island

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n1_4mer:GRV/n1_4mer:RV = (Global Relative Variance of OU patterns) / (Local Relative Variance of OU patterns)

n0_4mer:D = Distance between local and global OU patterns

n0_4mer:PS = Distance between 2 strands of same DNA molecule

Selected loci indicated by large D, increased GRV associated with decreased RV and moderate increase in PS

NC_006570: Francisella tularensis subsp. tularensis Schu 4, complete genome

NCBI: NC_006570

Host Lineage: Francisella tularensis; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria

General Information: This subspecies is virulent in humans, and the strain is a clinical isolate that is also virulent in an animal model. Originally isolated from a human case of tularemia in 1951. There are a large number of insertion sequences including a mariner element, which is a transposon typically found in eukaryotes and is the first instance of this element to be found in a microbe, which may have acquired it during transit through one of the insect vectors. Causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.

Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

#StartEndLengthIsland TextGRV_RVDPSNeighboursClusterSub ClusterBLASTNKey Word ConfirmationOther DB ConfirmationDownload Island
124636*7715752522Island text1.8002317.049629.4504Neighbours21BLASTN+24636.gbk
2141966*17413932174Island text1.6766118.628232.6021Neighbours21BLASTN+141966.gbk
3324974*35814633173Island text1.7888321.677338.1589NeighboursBLASTNIslandViewer 324974.gbk
4529426*55446125036Island text1.6595315.3730.8693Neighbours21BLASTN529426.gbk
565029167025419964Island text1.6007215.774626.6278Neighbours21BLASTN650291.gbk
6707280*73124223963Island text1.4922315.965526.6293Neighbours21BLASTN+707280.gbk
71405178*142352318346Island text1.4794616.038425.5634Neighbours21BLASTN PAI DB1405178.gbk
81526071*154588919819Island text1.7263615.674925.7918Neighbours21BLASTN+1526071.gbk
91577491160329325803Island text1.511616.69528.7733Neighbours21BLASTN1577491.gbk
101625909164817822270Island text1.6697816.823427.8505NeighboursBLASTN1625909.gbk
111794832181779222961Island text1.8686617.066630.0493NeighboursBLASTN PAI DB1794832.gbk