Pre_GI Gene

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Host: NC_006570 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_006570:650291 Francisella tularensis subsp. tularensis Schu 4, complete genome

Host Lineage: Francisella tularensis; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria

General Information: This subspecies is virulent in humans, and the strain is a clinical isolate that is also virulent in an animal model. Originally isolated from a human case of tularemia in 1951. There are a large number of insertion sequences including a mariner element, which is a transposon typically found in eukaryotes and is the first instance of this element to be found in a microbe, which may have acquired it during transit through one of the insect vectors. Causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
6502916515981308protease GTP-binding subunitQuickGO ontologyBLASTP
6516096527991191hypothetical proteinBLASTP
6529716540381068SPFH domain band 7 family proteinQuickGO ontologyBLASTP
654040654966927SPFH domain band 7 family proteinQuickGO ontologyBLASTP
654967655452486low molecular weight LMW phosphotyrosine protein phosphataseQuickGO ontologyBLASTP
655449656042594ATPGTP-binding proteinQuickGO ontologyBLASTP
657479657829351hypothetical proteinBLASTP
657871657981111hypothetical proteinBLASTP
6580056596601656dihydroxy-acid dehydrataseQuickGO ontologyBLASTP
661523661840318acetolactate synthase small subunitQuickGO ontologyBLASTP
6630356664603426Transcription-repair coupling factorATP-dependentQuickGO ontologyBLASTP
666505667191687hypothetical proteinBLASTP
6673076685661260hypothetical membrane proteinQuickGO ontologyBLASTP
668566668997432hypothetical proteinBLASTP
668994669632639Endonuclease IIIQuickGO ontologyBLASTP
669625670254630Iron-sulfur cluster-binding proteinQuickGO ontologyBLASTP