Pre_GI Gene

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Host: NC_006570 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_006570:1794832 Francisella tularensis subsp. tularensis Schu 4, complete genome

Host Lineage: Francisella tularensis; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria

General Information: This subspecies is virulent in humans, and the strain is a clinical isolate that is also virulent in an animal model. Originally isolated from a human case of tularemia in 1951. There are a large number of insertion sequences including a mariner element, which is a transposon typically found in eukaryotes and is the first instance of this element to be found in a microbe, which may have acquired it during transit through one of the insect vectors. Causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
179483217984193588hypothetical proteinBLASTP
180211718059893873phosphoribosylformylglycinamidine synthaseQuickGO ontologyBLASTP
180598918074791491amidophosphoribosyltransferaseQuickGO ontologyBLASTP
180757318089191347glutamate decarboxylaseQuickGO ontologyBLASTP
18089301809574645hypothetical proteinBLASTP
180958018111091530outer membrane protein tolC precursorQuickGO ontologyBLASTP
18111181811738621Protein-L-isoaspartate O-methyltransferaseQuickGO ontologyBLASTP
181205818133891332protease yegQQuickGO ontologyBLASTP
181343018146201191multidrug resistance protein membrane locatedQuickGO ontologyBLASTP
181478618162131428NaH antiporterQuickGO ontologyBLASTP