Pre_GI Gene

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Host: NC_006570 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_006570:1577491 Francisella tularensis subsp. tularensis Schu 4, complete genome

Host Lineage: Francisella tularensis; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria

General Information: This subspecies is virulent in humans, and the strain is a clinical isolate that is also virulent in an animal model. Originally isolated from a human case of tularemia in 1951. There are a large number of insertion sequences including a mariner element, which is a transposon typically found in eukaryotes and is the first instance of this element to be found in a microbe, which may have acquired it during transit through one of the insect vectors. Causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
157749115817594269ATp-dependent helicaseQuickGO ontologyBLASTP
15817831582670888hypothetical membrane proteinQuickGO ontologyBLASTP
158268415849272244isocitrate dehydrogenaseQuickGO ontologyBLASTP
15849311585296366arsenate reductaseQuickGO ontologyBLASTP
158551215872001689long chain fatty acid CoA ligaseQuickGO ontologyBLASTP
158721715894782262Acyl-CoA dehydrogenaseQuickGO ontologyBLASTP
158955115922472697fusion product of 3-hydroxacyl-CoA dehydrogenase and acyl-CoA-binding proteinQuickGO ontologyBLASTP
159226015934471188acetyl-CoA acetyltransferaseQuickGO ontologyBLASTP
15935091593997489hypothetical proteinBLASTP
159565715970721416hypothetical proteinBLASTP
15984151599329915hypothetical proteinBLASTP
159946916008631395hypothetical proteinBLASTP
16008691601852984hypothetical proteinBLASTP
160186316032931431hypothetical proteinBLASTP