Pre_GI Gene

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Host: NC_006570 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_006570:1625909 Francisella tularensis subsp. tularensis Schu 4, complete genome

Host Lineage: Francisella tularensis; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria

General Information: This subspecies is virulent in humans, and the strain is a clinical isolate that is also virulent in an animal model. Originally isolated from a human case of tularemia in 1951. There are a large number of insertion sequences including a mariner element, which is a transposon typically found in eukaryotes and is the first instance of this element to be found in a microbe, which may have acquired it during transit through one of the insect vectors. Causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
16259091626718810hypothetical proteinBLASTP
16285391628835297hypothetical proteinBLASTP
16290061629593588hypothetical membrane proteinQuickGO ontologyBLASTP
162965216307941143Lipid-A-disaccharide synthaseQuickGO ontologyBLASTP
16307941631573780UDP-N-acetylglucosamine acyltransferaseQuickGO ontologyBLASTP
163157616320674923R-hydroxymyristoyl-acyl-carrier protein dehydrataseQuickGO ontologyBLASTP
163208216330951014UDP-3-O-3-hydroxymyristoyl glucosamine N-acyltransferaseQuickGO ontologyBLASTP
16331141633617504outer membrane protein OmpHQuickGO ontologyBLASTP
163375316361312379outer membrane proteinQuickGO ontologyBLASTP
1636137163729411581-deoxy-D-xylulose 5-phosphate reductoisomeraseQuickGO ontologyBLASTP
163730016399062607DNA gyrase subunit AQuickGO ontologyBLASTP
16401651640710546hypothetical membrane proteinQuickGO ontologyBLASTP
164074616418311086hypothetical proteinBLASTP
16418661642528663uracil-DNA glycosylaseQuickGO ontologyBLASTP
164252516453982874Type III restriction enzymeQuickGO ontologyBLASTP
16456351646165531hypothetical proteinBLASTP
16462341646518285EndonucleaseQuickGO ontologyBLASTP