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Query: NC_006085:1859191:1879989 Propionibacterium acnes KPA171202, complete genome

Start: 1879989, End: 1880642, Length: 654

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Isolated from human skin. Acne causing bacterium. This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic.It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016511:1811171:183193118319311832581651Propionibacterium acnes TypeIA2 P.acn31 chromosome, completeuridine kinase6e-106383
NC_014039:1813205:183413818341381834656519Propionibacterium acnes SK137 chromosome, complete genomehypothetical protein6e-85313
NC_013530:423540:441608441608442273666Xylanimonas cellulosilytica DSM 15894, complete genomeUridine kinase-like protein3e-24112
NC_012803:1117875:113810911381091138729621Micrococcus luteus NCTC 2665, complete genomeuridine kinase2e-1995.9
NC_016582:5769080:579043757904375791099663Streptomyces bingchenggensis BCW-1 chromosome, complete genomeuridine kinase6e-1374.3