Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:5769080 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
57681065769083978hypothetical protein
576908057703121233monooxygenase FAD-binding proteinQuickGO ontologyBLASTP
57704305771146717TetR family transcriptional regulatorQuickGO ontologyBLASTP
577119257725231332hypothetical proteinBLASTP
577259957744971899PBS lyase HEAT domain-containing protein repeat-containing proteinQuickGO ontologyBLASTP
57746245774845222hypothetical proteinBLASTP
57748425775060219regulatory proteinQuickGO ontologyBLASTP
57750575775887831putative DNA-binding proteinQuickGO ontologyBLASTP
57761415776467327hypothetical proteinBLASTP
577649457803783885putative WD-40 repeat proteinQuickGO ontologyBLASTP
57806965781226531ECF subfamily RNA polymerase sigma factorQuickGO ontologyBLASTP
57814265782034609hypothetical proteinBLASTP
578263357847442112ATPGTP-binding proteinQuickGO ontologyBLASTP
57847795785354576lipoprotein signal peptidaseQuickGO ontologyBLASTP
57853965786097702integral membrane proteinQuickGO ontology
57862245786847624Lysine exporter protein LysEQuickGO ontologyBLASTP
578694557879611017deoxyribose-phosphate aldolaseQuickGO ontologyBLASTP
578796957894501482aldehyde dehydrogenaseQuickGO ontologyBLASTP
57894435790339897putative aldehyde dehydrogenaseQuickGO ontologyBLASTP
57904375791099663uridine kinaseQuickGO ontologyBLASTP
57913095791824516putative sigma factorQuickGO ontologyBLASTP