Pre_GI: BLASTN Hits

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Query: NC_009697:3409185 Clostridium botulinum A str. ATCC 19397 chromosome, complete

Start: 3409185, End: 3427472, Length: 18288

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum A ATCC 19397 (NCTC 4587, NCTC 7272) is a stock, type A toxin-producing, laboratory strain of known toxicity. Produces botulinum, one of the most potent toxins known. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin. Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_010520:3526883*3526883355123524353Clostridium botulinum A3 str. Loch Maree, complete genome02391BLASTN svgBLASTP svg
NC_021182:16549031654903167678221880Clostridium pasteurianum BC1, complete genome2e-120440BLASTN svgBLASTP svg
NC_018643:482676*48267650224119566Alpha proteobacterium HIMB5 chromosome, complete genome5e-35157BLASTN svgBLASTP svg
NC_014393:19016881901688192179720110Clostridium cellulovorans 743B chromosome, complete genome3e-21111BLASTN svgBLASTP svg
NC_007205:841818*84181886460622789Candidatus Pelagibacter ubique HTCC1062, complete genome6e-19103BLASTN svgBLASTP svg
NC_004722:4405363*4405363443759932237Bacillus cereus ATCC 14579, complete genome1e-1799.6BLASTN svgBLASTP svg
NC_009012:3224000*3224000324268718688Clostridium thermocellum ATCC 27405, complete genome2e-1695.6BLASTN svgBLASTP svg
NC_010001:47335447335449159918246Clostridium phytofermentans ISDg, complete genome6e-1693.7BLASTN svgBLASTP svg
NC_003997:4273579*4273579429175418176Bacillus anthracis str. Ames, complete genome2e-1591.7BLASTN svgBLASTP svg
NC_012225:25232622523262254758024319Brachyspira hyodysenteriae WA1, complete genome2e-1591.7BLASTN svgBLASTP svg
NC_003909:4831000*4831000485077119772Bacillus cereus ATCC 10987, complete genome9e-1589.7BLASTN svgBLASTP svg
NC_014335:4181710*4181710422264840939Bacillus cereus biovar anthracis str. CI chromosome, complete6e-1383.8BLASTN svgBLASTP svg
NC_012472:4255729*4255729429630140573Bacillus cereus 03BB102, complete genome6e-1383.8BLASTN svgBLASTP svg
NC_013171:41627941627944324226964Anaerococcus prevotii DSM 20548, complete genome2e-1281.8BLASTN svgBLASTP svg
NC_011126:129937*12993714809918163Hydrogenobaculum sp. Y04AAS1, complete genome2e-1281.8BLASTN svgBLASTP svg
NC_014499:87528*8752810905021523Candidatus Sulcia muelleri CARI chromosome, complete genome9e-1279.8BLASTN svgBLASTP svg
NC_015557:114648*11464815148336836Hydrogenobaculum sp. 3684 chromosome, complete genome9e-1279.8BLASTN svgBLASTP svg
NC_015587:114684*11468415151936836Hydrogenobaculum sp. SHO chromosome, complete genome9e-1279.8BLASTN svgBLASTP svg
NC_020411:114683*11468315151836836Hydrogenobaculum sp. HO, complete genome9e-1279.8BLASTN svgBLASTP svg
NC_002528:50595150595153093624986Buchnera aphidicola str. APS (Acyrthosiphon pisum), complete4e-1177.8BLASTN svgBLASTP svg
NC_011653:1226035*1226035125859932565Thermosipho africanus TCF52B, complete genome6e-1073.8BLASTN svgBLASTP svg
NC_012440:1215838*1215838124846532628Persephonella marina EX-H1, complete genome2e-0971.9BLASTN svgBLASTP svg
NC_011772:4397599*4397599441737119773Bacillus cereus G9842, complete genome2e-0971.9BLASTN svgBLASTP svg
NC_008600:4263505*4263505428734423840Bacillus thuringiensis str. Al Hakam, complete genome2e-0971.9BLASTN svgBLASTP svg
NC_014004:66631*666318870622076Candidatus Sulcia muelleri DMIN chromosome, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_019970:81391781391783706923153Thermoanaerobacterium thermosaccharolyticum M0795, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_015391:1323171*1323171134609922929Carnobacterium sp. 17-4 chromosome, complete genome5e-0763.9BLASTN svgBLASTP svg
NC_003909:4209385*4209385423241623032Bacillus cereus ATCC 10987, complete genome5e-0763.9BLASTN svgBLASTP svg
NC_015682:736746*73674676603529290Thermodesulfobacterium sp. OPB45 chromosome, complete genome8e-0660BLASTN svgBLASTP svg
NC_015555:1450704*1450704146842117718Thermoanaerobacterium xylanolyticum LX-11 chromosome, complete8e-0660BLASTN svgBLASTP svg
NC_011661:1100576*1100576112031619741Dictyoglomus turgidum DSM 6724, complete genome8e-0660BLASTN svgBLASTP svg
NC_010003:1577934*1577934159579517862Petrotoga mobilis SJ95, complete genome8e-0660BLASTN svgBLASTP svg
NC_008710:621822*62182266159939778Borrelia turicatae 91E135, complete genome8e-0660BLASTN svgBLASTP svg