Pre_GI: BLASTP Hits

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Query: NC_009142:1242850:1244426 Saccharopolyspora erythraea NRRL 2338, complete genome

Start: 1244426, End: 1245748, Length: 1323

Host Lineage: Saccharopolyspora erythraea; Saccharopolyspora; Pseudonocardiaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Source of the antibiotic erythromycin. Saccharopolyspora erythraea is the soil bacterium that produces the industrially important antibiotic erythromycin A. Erythromycin is a clinically important and potent macrolide antibiotic. It is used to treat infections caused by several prokaryotic pathogens such as Streptococcus, Staphylococcus, Mycoplasma, Ureaplasma, Chlamydia and Legionella. Production of this antibiotic is lower than others in the same class, such as penicillin or cephalosporin, which has led to the development of a genetic system to attempt to enhance the production of erythromycin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_019673:1039258:1059925105992510613011377Saccharothrix espanaensis DSM 44229 complete genomePhenylacetate-CoA ligase9e-128457
NC_013093:1036772:1062951106295110642551305Actinosynnema mirum DSM 43827, complete genomePhenylacetate--CoA ligase1e-124446
NC_016627:1960097:1982156198215619834601305Clostridium clariflavum DSM 19732 chromosome, complete genomecoenzyme F390 synthetase8e-87321
NC_011979:3045952:3065023306502330663271305Geobacter sp. FRC-32, complete genomePhenylacetate--CoA ligase1e-82307
NC_009483:2489000:2490625249062524919291305Geobacter uraniireducens Rf4 chromosome, complete genomephenylacetate--CoA ligase3e-82305
NC_020409:363114:3655483655483668521305Desulfovibrio piezophilus str. nov C1TLV30 chromosome, completePhenylacetate-coenzyme A ligase1e-80300
NC_014228:4408500:4419780441978044211231344Xenorhabdus nematophila ATCC 19061, complete genomephenylacetyl-CoA ligase, phenylacetic acid degradation6e-76285
NC_015499:1493500:1504803150480315061101308Thermodesulfobium narugense DSM 14796 chromosome, complete genomePhenylacetate--CoA ligase2e-73276
NC_018691:896464:9006069006069019011296Alcanivorax dieselolei B5 chromosome, complete genomePhenylacetate-CoA ligase8e-73274
NC_013890:808791:8136918136918150101320Dehalococcoides sp. GT chromosome, complete genomePhenylacetate--CoA ligase9e-72271
NC_013892:114884:1197261197261210331308Xenorhabdus bovienii SS-2004 chromosome, complete genomephenylacetyl-CoA ligase, phenylacetic acid degradation2e-71270
NC_014722:1084616:1084616108461610859231308Burkholderia rhizoxinica HKI 454, complete genomeCoenzyme F390 Synthetase / phenylacetate-coenzyme A ligase2e-71270
NC_013849:1034472:1056461105646110577561296Ferroglobus placidus DSM 10642 chromosome, complete genomeAMP-dependent synthetase and ligase3e-71269
NC_015499:1493500:1500640150064015019441305Thermodesulfobium narugense DSM 14796 chromosome, complete genomePhenylacetate--CoA ligase3e-71269
NC_017272:921193:9211939211939225271335Thermus thermophilus SG0.5JP17-16 chromosome, complete genomephenylacetate--CoA ligase8e-71268
NC_018876:2604055:2617254261725426185581305Methanolobus psychrophilus R15 chromosome, complete genomephenylacetate-CoA ligase9e-70264
NC_002570:207555:2130302130302143671338Bacillus halodurans C-125, complete genomephenylacetyl-CoA ligase in the phenylacetic acid catabolic pathway2e-69263
NC_011894:3475775:3482117348211734834481332Methylobacterium nodulans ORS 2060, complete genomephenylacetate-CoA ligase3e-69263
NC_011979:3070110:3072583307258330738871305Geobacter sp. FRC-32, complete genomePhenylacetate--CoA ligase1e-68261
NC_015733:2963548:2985941298594129872601320Pseudomonas putida S16 chromosome, complete genomephenylacetate-CoA ligase1e-67257
NC_015638:1824794:1844428184442818457141287Lacinutrix sp. 5H-3-7-4 chromosome, complete genomePhenylacetate--CoA ligase2e-66253
NC_020302:3014483:3038969303896930402821314Corynebacterium halotolerans YIM 70093 = DSM 44683, completephenylacetate-CoA ligase1e-62241
NC_014253:575360:5820365820365833371302Methanohalobium evestigatum Z-7303 chromosome, complete genomePhenylacetate--CoA ligase1e-61237
NC_003552:4714457:4734881473488147361851305Methanosarcina acetivorans C2A, complete genomecoenzyme F390 synthetase5e-61235
NC_016027:2512297:2534465253446525357931329Gluconacetobacter xylinus NBRC 3288, complete genomephenylacetate-CoA ligase3e-60233
NC_009712:669647:6724826724826737831302Candidatus Methanoregula boonei 6A8, complete genomephenylacetate--CoA ligase5e-60232
NC_009712:669647:6737836737836750541272Candidatus Methanoregula boonei 6A8, complete genomephenylacetate--CoA ligase5e-59228
NC_015500:2329957:2352706235270623540281323Treponema brennaborense DSM 12168 chromosome, complete genomePhenylacetate--CoA ligase7e-56218
NC_015499:1640500:1654187165418716554491263Thermodesulfobium narugense DSM 14796 chromosome, complete genomePhenylacetate--CoA ligase1e-55217
NC_015578:2026741:2074357207435720757031347Treponema primitia ZAS-2 chromosome, complete genomephenylacetate-coenzyme A ligase4e-51202
NC_016629:415711:4356054356054368971293Desulfovibrio africanus str. Walvis Bay chromosome, completephenylacetate--CoA ligase8e-51201
NC_013170:311045:3116743116743129121239Cryptobacterium curtum DSM 15641, complete genomephenylacetate-CoA ligase8e-49194
NC_013204:74855:7619876198774391242Eggerthella lenta DSM 2243, complete genomePhenylacetate--CoA ligase2e-47190
NC_013741:302415:3191133191133203631251Archaeoglobus profundus DSM 5631, complete genomePhenylacetate--CoA ligase8e-46184
NC_009943:970901:9719049719049731991296Candidatus Desulfococcus oleovorans Hxd3, complete genomePhenylacetate--CoA ligase1e-44181
NC_012623:2680601:2697343269734326986501308Sulfolobus islandicus Y.N.15.51 chromosome, complete genomephenylacetate--CoA ligase9e-41168
NC_017275:2519637:2538063253806325393701308Sulfolobus islandicus HVE10/4 chromosome, complete genomephenylacetate-CoA ligase8e-41168
NC_017276:2391645:2410071241007124113781308Sulfolobus islandicus REY15A chromosome, complete genomephenylacetate--CoA ligase8e-41168
NC_012632:2564801:2583227258322725845341308Sulfolobus islandicus M.16.27 chromosome, complete genomephenylacetate--CoA ligase1e-40167
NC_012588:2483000:2499134249913425004411308Sulfolobus islandicus M.14.25 chromosome, complete genomephenylacetate--CoA ligase1e-40167
NC_012726:2461102:2479528247952824808351308Sulfolobus islandicus M.16.4 chromosome, complete genomephenylacetate--CoA ligase1e-40167
NC_012622:2571812:2590640259064025919471308Sulfolobus islandicus Y.G.57.14 chromosome, complete genomephenylacetate--CoA ligase1e-40167
NC_012589:2605085:2621829262182926231361308Sulfolobus islandicus L.S.2.15, complete genomePhenylacetate--CoA ligase1e-40167
NC_002754:2391867:2392154239215423931731020Sulfolobus solfataricus P2, complete genomeCoA-ligase / coenzyme F390 synthetase, putative1e-37157
NC_016885:1153277:1162327116232711636311305Pyrobaculum oguniense TE7 chromosome, complete genomeCoenzyme F390 synthetase1e-36154
NC_016627:3158353:3166226316622631675451320Clostridium clariflavum DSM 19732 chromosome, complete genomecoenzyme F390 synthetase4e-31135
NC_008148:1859888:1867573186757318688951323Rubrobacter xylanophilus DSM 9941, complete genomePhenylacetate--CoA ligase9e-31134
NC_006513:1379735:1412255141225514136491395Azoarcus sp. EbN1, complete genomepossible benzoylacetate-CoA ligase1e-29131
NC_015275:4577642:4586034458603445873501317Clostridium lentocellum DSM 5427 chromosome, complete genomePhenylacetate--CoA ligase6e-29129
NC_008148:1859888:1876471187647118778201350Rubrobacter xylanophilus DSM 9941, complete genomePhenylacetate--CoA ligase3e-28126
NC_015422:1694363:1718192171819217195531362Alicycliphilus denitrificans K601 chromosome, complete genomePhenylacetate--CoA ligase2e-26120
NC_008699:2260606:2277546227754622789641419Nocardioides sp. JS614, complete genomePhenylacetate--CoA ligase4e-24112
NC_015656:3200500:3211392321139232127711380Frankia symbiont of Datisca glomerata chromosome, complete genomePhenylacetate--CoA ligase9e-2098.6
NC_021184:3912805:3924377392437739257111335Desulfotomaculum gibsoniae DSM 7213, complete genomecoenzyme F390 synthetase1e-1791.3
NC_014623:7482229:7496365749636574976961332Stigmatella aurantiaca DW4/3-1 chromosome, complete genomephenylacetate-CoA ligase2e-1480.5
NC_014844:3469848:3475669347566934769341266Desulfovibrio aespoeensis Aspo-2 chromosome, complete genomeAMP-dependent synthetase and ligase4e-1479.7
NC_016803:2431672:2436907243690724381721266Desulfovibrio desulfuricans ND132 chromosome, complete genomeAMP-dependent synthetase and ligase1e-1378.6
NC_014551:2510000:2525555252555525268771323Bacillus amyloliquefaciens DSM 7, complete genomeCoenzyme F390 synthetase1e-1274.3
NC_009092:3057319:3070906307090630721321227Shewanella loihica PV-4, complete genomeputative phenylacetate-coenzyme A ligase3e-1273.2
NC_009051:657000:6658626658626671421281Methanoculleus marisnigri JR1, complete genomeCapK related-protein4e-1273.2
NC_014328:2643588:2651432265143226527451314Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative AMP-binding protein2e-1171.2
NC_007953:938346:9538109538109552221413Burkholderia xenovorans LB400 chromosome 3, complete sequencePutative coenzyme F390 synthetase II6e-1168.9
NC_014931:6203872:6208513620851362097571245Variovorax paradoxus EPS chromosome, complete genomeAMP-dependent synthetase and ligase1e-0964.7
NC_016610:795903:8005968005968019151320Tannerella forsythia ATCC 43037 chromosome, complete genomehypothetical protein2e-0963.9
NC_008786:3045770:3063888306388830651291242Verminephrobacter eiseniae EF01-2, complete genomeputative phenylacetate-CoA ligase1e-0861.6
NC_007517:1998342:2014298201429820156501353Geobacter metallireducens GS-15, complete genomeCoenzyme F390 synthetase-like2e-0860.8
NC_008554:1623041:1624450162445016257781329Syntrophobacter fumaroxidans MPOB, complete genomehypothetical protein4e-0859.7
NC_013216:3625830:3632210363221036336131404Desulfotomaculum acetoxidans DSM 771, complete genomecoenzyme F390 synthetase-like protein4e-0756.6
NC_017030:9028412:9045670904567090474271758Corallococcus coralloides DSM 2259 chromosome, complete genomeAMP-binding protein4e-0756.6
NC_007298:2568851:2601271260127126026261356Dechloromonas aromatica RCB, complete genomepossible CapK protein1e-0654.7
NC_012654:18893:3274132741340061266Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequencephenylacetate--CoA ligase1e-0654.7
NC_002488:1812696:1821986182198618234221437Xylella fastidiosa 9a5c, complete genomecoenzyme F390 synthetase4e-0653.1