Pre_GI: BLASTP Hits

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Query: NC_005957:4472800:4488332 Bacillus thuringiensis serovar konkukian str. 97-27, complete

Start: 4488332, End: 4488643, Length: 312

Host Lineage: Bacillus thuringiensis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This organism was isolated from a case of severe human tissue necrosis which is unusual since human infections by this organism are rare. Produces insect toxinT his organism, also known as BT, is famous for the production of an insecticidal toxin. The bacterium was initially discovered as a pathogen of various insects and was first used as an insecticidal agent in the early part of this century. This organism, like many other Bacilli, is found in the soil, where it leads a saprophytic existence, but becomes an opportunistic pathogen of insects when ingested. The specific activity of the toxin towards insects and its lack of toxicity to animals has made this organism a useful biocontrol agent. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The presence of a parasporal crystal, which is outside the exosporium of the endospore, is indicative of production of the toxin, and serves as a marker for this species.Activation of the toxin typically requires a high pH environment such as the alkaline environments in insect midguts followed by proteolysis. Various toxin genes specific for a variety of insects have been studied, and many are now being used in genetically modified plants which have been engineered to produce the toxin themselves, eliminating the need to produce sufficient amounts of B. thuringiensis spores.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_011969:4396000:441570844157084416019312Bacillus cereus Q1 chromosome, complete genomehypothetical protein5e-43172
NC_011773:4541306:455676045567604557071312Bacillus cereus AH820 chromosome, complete genomehypothetical protein5e-43172
NC_017208:4662500:467783446778344678145312Bacillus thuringiensis serovar chinensis CT-43 chromosome, completehypothetical protein2e-42171
NC_011772:4606000:462280446228044623115312Bacillus cereus G9842, complete genomehypothetical protein2e-42171
NC_014335:4414052:442724644272464427557312Bacillus cereus biovar anthracis str. CI chromosome, completehypothetical protein2e-42170
NC_007530:4474000:449338144933814493692312Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein4e-42169
NC_003997:4473973:449325444932544493565312Bacillus anthracis str. Ames, complete genomehypothetical protein4e-42169
NC_012581:4478036:449480544948054495116312Bacillus anthracis str. CDC 684 chromosome, complete genomehypothetical protein4e-42169
NC_012659:4474000:449328144932814493592312Bacillus anthracis str. A0248, complete genomehypothetical protein4e-42169
NC_010184:4497473:451801845180184518329312Bacillus weihenstephanensis KBAB4, complete genomePropeptide PepSY amd peptidase M43e-41166