Pre_GI: OUP Neighbours

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Query: NC_008767:2010140 Neisseria meningitidis FAM18, complete genome

D: 28.8941

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Isolated from a patient with meningococcal septicemia. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

Number of Neighbours: 11

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandSubject Host Description Compositional Similarity Proposed Island FlowSubject Island D
NC_003112:719490*Neisseria meningitidis MC58, complete genome80.2788 %Subject ←→ Query28.7847
NC_008767:1363288Neisseria meningitidis FAM18, complete genome81.3419 %Subject ←→ Query29.3714
NC_003116:867943*Neisseria meningitidis Z2491, complete genome80.5147 %Subject ←→ Query30.6025
NC_002946:1020175Neisseria gonorrhoeae FA 1090, complete genome76.9853 %Subject ←→ Query30.7269
NC_010120:662969*Neisseria meningitidis 053442, complete genome79.0165 %Subject ←→ Query31.0023
NC_010120:199942Neisseria meningitidis 053442, complete genome93.5018 %Subject ←→ Query31.098
NC_014752:23601*Neisseria lactamica ST-640, complete genome79.4393 %Subject ←→ Query31.1254
NC_007498:2618131*Pelobacter carbinolicus DSM 2380, complete genome75.1808 %Subject ←→ Query31.247
NC_003112:603879*Neisseria meningitidis MC58, complete genome76.9393 %Subject ←→ Query32.7335
NC_007498:3085511*Pelobacter carbinolicus DSM 2380, complete genome75.3707 %Subject ←→ Query33.6029
NC_014752:131994*Neisseria lactamica ST-640, complete genome76.1397 %Subject ←→ Query35.1775