Pre_GI Gene

Some Help

Host: NC_003112 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_003112:719490 Neisseria meningitidis MC58, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The B serogroup is responsible for many of the meningitis outbreaks in the developed world. This strain was isolated from a case of invasive infection. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
7194907207641275folylpolyglutamate synthasedihydrofolate synthaseQuickGO ontologyBLASTP
720795721241447folI proteinQuickGO ontologyBLASTP
721246721605360hypothetical proteinBLASTP
721678722406729amino acid ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
722579723358780dimethyladenosine transferaseQuickGO ontologyBLASTP
723555724244690hypothetical proteinBLASTP
7243277255291203tryptophan synthase subunit betaQuickGO ontologyBLASTP
7257087311555448IgA-specific serine endopeptidaseQuickGO ontologyBLASTP
731314731568255hypothetical protein
7325667346412076competence protein ComAQuickGO ontologyBLASTP
734869735672804competence lipoprotein ComLQuickGO ontologyBLASTP
7356717367951125ribosomal large subunit pseudouridine synthase DQuickGO ontologyBLASTP
736948737895948transporterQuickGO ontologyBLASTP
738455739234780hypothetical proteinBLASTP
739286739765480putative rare lipoprotein BQuickGO ontologyBLASTP
739767740765999DNA polymerase III subunit deltaQuickGO ontologyBLASTP
740886741305420hypothetical proteinBLASTP
741330741896567hypothetical proteinBLASTP
741980742864885hypothetical proteinBLASTP