Pre_GI Island

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n1_4mer:GRV/n1_4mer:RV = (Global Relative Variance of OU patterns) / (Local Relative Variance of OU patterns)

n0_4mer:D = Distance between local and global OU patterns

n0_4mer:PS = Distance between 2 strands of same DNA molecule

Selected loci indicated by large D, increased GRV associated with decreased RV and moderate increase in PS

NC_010120: Neisseria meningitidis 053442, complete genome

NCBI: NC_010120

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

#StartEndLengthIsland TextGRV_RVDPSNeighboursClusterSub ClusterBLASTNKey Word ConfirmationOther DB ConfirmationDownload Island
1144000*16559921600Island text1.5397832.492136.7246Neighbours24BLASTN+144000.gbk
219994222285022909Island text1.4811331.09847.789Neighbours35BLASTN+199942.gbk
345277147660723837Island text1.5138631.737424.5826Neighbours24BLASTNIslandViewer 452771.gbk
4609323*63703227710Island text1.9630633.125436.9061Neighbours24BLASTN609323.gbk
5662969*68275319785Island text1.5554931.002347.4464Neighbours35BLASTN662969.gbk
678800081026622267Island text1.5726333.086141.7651Neighbours35BLASTN788000.gbk
71065833109411728285Island text3.2664241.365521.0372Neighbours24BLASTN+IslandViewer 1065833.gbk
81313500133123817739Island text1.525631.505417.3712Neighbours24BLASTN+IslandViewer 1313500.gbk
91814592*183677422183Island text1.7785130.155634.9686Neighbours35BLASTN+1814592.gbk
102029880*205559925720Island text2.0470140.730545.3183Neighbours35BLASTN+IslandViewer 2029880.gbk
112055803*208173125929Island text1.4239534.089337.3005Neighbours35BLASTN2055803.gbk
122098000*212739829399Island text2.5130438.097431.6443Neighbours35BLASTN+IslandViewer 2098000.gbk