Pre_GI Gene

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Host: NC_010120 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_010120:452771 Neisseria meningitidis 053442, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.


StartEndLengthCDS descriptionQuickGO ontologyBLASTP
4527714542641494putative ribonucleases G cytoplasmic axial filament proteinQuickGO ontologyBLASTP
454453454734282glutaredoxin 3QuickGO ontologyBLASTP
454755455198444protein-export proteinQuickGO ontologyBLASTP
4552844573262043DNA helicaseQuickGO ontologyBLASTP
4581514591941044N-acetyl-gamma-glutamyl-phosphate reductaseQuickGO ontologyBLASTP
459191459484294conserved hypothetical proteinBLASTP
459508459639132conserved hypothetical protein
459852460172321conserved hypothetical proteinBLASTP
460191461000810conserved hypothetical proteinBLASTP
461229461582354conserved hypothetical proteinBLASTP
463183463350168conserved hypothetical proteinBLASTP
4637494654911743hemolysin activation protein HecB putativeQuickGO ontologyBLASTP
471688472197510conserved hypothetical proteinBLASTP
4722394739451707conserved hypothetical proteinBLASTP
473954474331378conserved hypothetical proteinBLASTP
474609474983375conserved hypothetical proteinBLASTP
4750184766071590conserved hypothetical proteinBLASTP