Pre_GI Gene

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Host: NC_010120 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_010120:144000 Neisseria meningitidis 053442, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.


This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
144568144801234conserved hypothetical protein
144801145739939ABC-transport system ATP-binding proteinQuickGO ontologyBLASTP
1457481467701023thiamin pyrophosphokinase-related proteinQuickGO ontologyBLASTP
1472231491241902thiamin biosynthesis proteinQuickGO ontologyBLASTP
149927150883957putative invertasetransposaseQuickGO ontologyBLASTP
1510981522041107conserved hypothetical proteinBLASTP
152286152570285putative integral membrane proteinQuickGO ontologyBLASTP
1535151550741560TspB proteinQuickGO ontologyBLASTP
155493155795303conserved hypothetical proteinBLASTP
155823156053231conserved hypothetical proteinBLASTP
156291156491201conserved hypothetical proteinBLASTP
156495156806312conserved hypothetical proteinBLASTP
1568181580321215conserved hypothetical proteinBLASTP
159502159738237conserved hypothetical proteinBLASTP
159864160862999porin major outer membrane protein PIQuickGO ontologyBLASTP
162664162981318PEMK-like proteinQuickGO ontologyBLASTP
162975163214240conserved hypothetical protein
163337164134798tRNA pseudouridine synthaseQuickGO ontologyBLASTP
164762165007246conserved hypothetical proteinBLASTP