Pre_GI Gene

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Host: NC_010120 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_010120:1065833 Neisseria meningitidis 053442, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
106583310673291497inosine-5-monophosphate dehydrogenaseQuickGO ontologyBLASTP
10676231068084462conserved hypothetical protein
106817410707322559protein-PII uridylyltransferaseQuickGO ontologyBLASTP
10707801071133354transcriptional regulatorQuickGO ontologyBLASTP
10714251071898474bacterioferritin BQuickGO ontologyBLASTP
10719261072360435bacterioferritin AQuickGO ontologyBLASTP
10724331072618186conserved hypothetical protein
10735041073923420putative ATP-binding proteinQuickGO ontologyBLASTP
107474510762891545conserved hypothetical proteinBLASTP
10762861077158873putative ATP-binding proteinQuickGO ontologyBLASTP
107759210786141023modification methylase cytosine-specific DNA methylaseQuickGO ontologyBLASTP
10825461083514969lipoic acid synthetaseQuickGO ontologyBLASTP
10835071084130624lipoate-protein ligase BQuickGO ontologyBLASTP
10841331084354222conserved hypothetical proteinBLASTP
10843021084535234conserved hypothetical proteinBLASTP
108459310856631071transporter putativeQuickGO ontologyBLASTP
10858591086494636stomatinMec-2 family proteinQuickGO ontologyBLASTP
10865591087329771membrane proteinQuickGO ontologyBLASTP
10873081087967660uracil-DNA glycosylaseQuickGO ontologyBLASTP
10894521089598147transposaseQuickGO ontologyBLASTP
10912141091729516periplasmic proteinQuickGO ontologyBLASTP
10919181092208291conserved hypothetical proteinBLASTP
109219510941171923ABC transporter ATP-binding proteinQuickGO ontologyBLASTP