Pre_GI Island

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n1_4mer:GRV/n1_4mer:RV = (Global Relative Variance of OU patterns) / (Local Relative Variance of OU patterns)

n0_4mer:D = Distance between local and global OU patterns

n0_4mer:PS = Distance between 2 strands of same DNA molecule

Selected loci indicated by large D, increased GRV associated with decreased RV and moderate increase in PS

NC_002935: Corynebacterium diphtheriae NCTC 13129, complete genome

NCBI: NC_002935

Host Lineage: Corynebacterium diphtheriae; Corynebacterium; Corynebacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated in 1997 from the pharyngeal membrane of a 72-year-old unimmunized UK female with clinical diphtheria acquired during a short Baltic cruise. Causative agent of diphtheria. They may be found as members of the normal microflora of humans, where these bacteria find a suitable niche in virtually every anatomic site. This organism is the best known and most widely studied species of the genus. It is the causal agent of the disease diphtheria, a deadly infectious disease spreading from person to person by respiratory droplets from the throat through coughing and sneezing. In the course of infection, the bacteria invade and colonize tissues of the upper respiratory tract, proliferate and produce exotoxin that inhibits protein synthesis and causes local lesions and systemic degenerative changes in the heart, muscles, peripheral nerves, liver and other vital organs. In 1951, Victor Freeman discovered that pathogenic (toxigenic) strains. Moreover, later it was found that the gene for toxin production is located in the DNA of the B-type phage.

Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

#StartEndLengthIsland TextGRV_RVDPSNeighboursClusterSub ClusterBLASTNKey Word ConfirmationOther DB ConfirmationDownload Island
148687*6982821142Island text1.6746534.653513.068Neighbours11BLASTN+IslandViewer 48687.gbk
2181902*20033418433Island text1.6113536.986355.7985Neighbours14BLASTN+IslandViewer 181902.gbk
3781172*80470523534Island text1.5718533.694115.7388Neighbours11BLASTN+IslandViewer 781172.gbk
41237585*131159974015Island text1.6522835.020729.5357Neighbours17BLASTN+1237585.gbk
51315019*137072155703Island text1.7436634.564837.2742Neighbours17BLASTNIslandViewer 1315019.gbk
61378566*145023271667Island text1.7799134.655530.9492Neighbours17BLASTN+IslandViewer 1378566.gbk
71461458*148363322176Island text1.7565235.45624.1383Neighbours17BLASTN+IslandViewer 1461458.gbk
81534889*155553420646Island text1.6947734.285832.8578Neighbours17BLASTN+1534889.gbk
91763886178625222367Island text1.7638333.797443.5193Neighbours19+1763886.gbk
102059672207754417873Island text1.9125232.274452.4881BLASTN+IslandViewer 2059672.gbk
112103677212647322797Island text1.7224636.89248.4956Neighbours14BLASTNIslandViewer 2103677.gbk
122292835231381620982Island text1.873835.985143.3171BLASTN2292835.gbk