Pre_GI Gene

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Host: NC_002935 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_002935:1763886 Corynebacterium diphtheriae NCTC 13129, complete genome

Host Lineage: Corynebacterium diphtheriae; Corynebacterium; Corynebacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated in 1997 from the pharyngeal membrane of a 72-year-old unimmunized UK female with clinical diphtheria acquired during a short Baltic cruise. Causative agent of diphtheria. They may be found as members of the normal microflora of humans, where these bacteria find a suitable niche in virtually every anatomic site. This organism is the best known and most widely studied species of the genus. It is the causal agent of the disease diphtheria, a deadly infectious disease spreading from person to person by respiratory droplets from the throat through coughing and sneezing. In the course of infection, the bacteria invade and colonize tissues of the upper respiratory tract, proliferate and produce exotoxin that inhibits protein synthesis and causes local lesions and systemic degenerative changes in the heart, muscles, peripheral nerves, liver and other vital organs. In 1951, Victor Freeman discovered that pathogenic (toxigenic) strains. Moreover, later it was found that the gene for toxin production is located in the DNA of the B-type phage.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
176388617657151830Putative long-chain-fatty-acid-CoA ligaseQuickGO ontologyBLASTP
176581217679802169Putative glucanotransferaseQuickGO ontologyBLASTP
17681271768330204hypothetical proteinBLASTP
176832717703061980Putative peptidaseQuickGO ontologyBLASTP
177033517715341200Putative drug resistance protein hydrolaseQuickGO ontologyBLASTP
17715211772072552isopentenyl-diphosphate delta-isomeraseQuickGO ontologyBLASTP
177209117736651575hypothetical proteinBLASTP
17736661774244579Putative secreted proteinQuickGO ontologyBLASTP
177450117756581158hypothetical proteinBLASTP
17758401776250411hypothetical proteinBLASTP
177646817783151848Putative ABC transport system ATP-binding membrane proteinQuickGO ontologyBLASTP
177833417794641131beta C-S lyaseQuickGO ontologyBLASTP
177954517808491305branched-chain amino acid ABC transport system membrane proteinQuickGO ontologyBLASTP
17808591781812954hypothetical proteinBLASTP
178179017836161827Ectoine glycine betaine and proline transport system membrane proteinQuickGO ontologyBLASTP
178377217852981527Putative ABC transport system solute-binding secreted proteinQuickGO ontologyBLASTP
17853051786252948Putative oligopeptide ABC transport system membrane proteinQuickGO ontologyBLASTP