Pre_GI Gene

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Host: NC_002935 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_002935:181902 Corynebacterium diphtheriae NCTC 13129, complete genome

Host Lineage: Corynebacterium diphtheriae; Corynebacterium; Corynebacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated in 1997 from the pharyngeal membrane of a 72-year-old unimmunized UK female with clinical diphtheria acquired during a short Baltic cruise. Causative agent of diphtheria. They may be found as members of the normal microflora of humans, where these bacteria find a suitable niche in virtually every anatomic site. This organism is the best known and most widely studied species of the genus. It is the causal agent of the disease diphtheria, a deadly infectious disease spreading from person to person by respiratory droplets from the throat through coughing and sneezing. In the course of infection, the bacteria invade and colonize tissues of the upper respiratory tract, proliferate and produce exotoxin that inhibits protein synthesis and causes local lesions and systemic degenerative changes in the heart, muscles, peripheral nerves, liver and other vital organs. In 1951, Victor Freeman discovered that pathogenic (toxigenic) strains. Moreover, later it was found that the gene for toxin production is located in the DNA of the B-type phage.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
181902182762861immunity-specific protein Beta286QuickGO ontologyBLASTP
1827621838771116immunity-specific protein Beta371QuickGO ontologyBLASTP
1838771853041428Putative phage tail fiber proteinQuickGO ontologyBLASTP
185304185978675hypothetical protein
1860591874981440hypothetical proteinBLASTP
187501187824324hypothetical proteinBLASTP
187830188294465hypothetical proteinBLASTP
188291188629339Putative secreted proteinQuickGO ontologyBLASTP
1889791906611683Diphtheria toxin precursorQuickGO ontologyBLASTP
19070919078880tRNA-ArgQuickGO ontology
190816190992177hypothetical proteinBLASTP
191070191210141hypothetical protein
1912201926261407Putative secreted polysaccharide deacetylaseQuickGO ontologyBLASTP
1926141939871374Putative GntR-family regulatorQuickGO ontologyBLASTP
194078194971894pyridoxine biosynthesis proteinQuickGO ontologyBLASTP
194965195522558Putative amidotransferaseQuickGO ontologyBLASTP
195519195686168hypothetical protein
197202197330129hypothetical protein
197338198327990Putative fimbrial associated sortase-like proteinQuickGO ontologyBLASTP
198371198847477hypothetical protein
1988622003341473Putative fimbrial subunitQuickGO ontologyBLASTP