Pre_GI Gene

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Host: NC_002935 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_002935:781172 Corynebacterium diphtheriae NCTC 13129, complete genome

Host Lineage: Corynebacterium diphtheriae; Corynebacterium; Corynebacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated in 1997 from the pharyngeal membrane of a 72-year-old unimmunized UK female with clinical diphtheria acquired during a short Baltic cruise. Causative agent of diphtheria. They may be found as members of the normal microflora of humans, where these bacteria find a suitable niche in virtually every anatomic site. This organism is the best known and most widely studied species of the genus. It is the causal agent of the disease diphtheria, a deadly infectious disease spreading from person to person by respiratory droplets from the throat through coughing and sneezing. In the course of infection, the bacteria invade and colonize tissues of the upper respiratory tract, proliferate and produce exotoxin that inhibits protein synthesis and causes local lesions and systemic degenerative changes in the heart, muscles, peripheral nerves, liver and other vital organs. In 1951, Victor Freeman discovered that pathogenic (toxigenic) strains. Moreover, later it was found that the gene for toxin production is located in the DNA of the B-type phage.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
7811727837242553hypothetical proteinBLASTP
7837287857312004Putative DNA methylaseQuickGO ontologyBLASTP
786230786958729hypothetical proteinBLASTP
786955787392438hypothetical protein
787574787945372hypothetical protein
787932788174243hypothetical protein
788227788601375hypothetical protein
788588788956369hypothetical proteinBLASTP
788946789917972hypothetical proteinBLASTP
789916790419504hypothetical protein
790442790960519hypothetical proteinBLASTP
7909537920171065Putative phage integraseQuickGO ontologyBLASTP
792350792688339Hypothetical protein putative DNA-binding proteinQuickGO ontology
792701793471771hypothetical proteinBLASTP
7935227953001779hypothetical proteinBLASTP
79554079561273tRNA-ArgQuickGO ontologyBLASTP
795749796081333hypothetical proteinBLASTP
796088796840753precorrin 6A synthaseQuickGO ontologyBLASTP
796859797116258hypothetical proteinBLASTP
797137797640504Putative folate reductaseQuickGO ontologyBLASTP
797640798452813thymidylate synthaseQuickGO ontologyBLASTP
798546799304759Putative sulfite synthesis related proteinQuickGO ontologyBLASTP
7993438041574815Putative ATP-dependent helicaseQuickGO ontologyBLASTP
804154804705552Putative DNA repair proteinQuickGO ontologyBLASTP