Pre_GI Gene

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Host: NC_002935 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_002935:2292835 Corynebacterium diphtheriae NCTC 13129, complete genome

Host Lineage: Corynebacterium diphtheriae; Corynebacterium; Corynebacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated in 1997 from the pharyngeal membrane of a 72-year-old unimmunized UK female with clinical diphtheria acquired during a short Baltic cruise. Causative agent of diphtheria. They may be found as members of the normal microflora of humans, where these bacteria find a suitable niche in virtually every anatomic site. This organism is the best known and most widely studied species of the genus. It is the causal agent of the disease diphtheria, a deadly infectious disease spreading from person to person by respiratory droplets from the throat through coughing and sneezing. In the course of infection, the bacteria invade and colonize tissues of the upper respiratory tract, proliferate and produce exotoxin that inhibits protein synthesis and causes local lesions and systemic degenerative changes in the heart, muscles, peripheral nerves, liver and other vital organs. In 1951, Victor Freeman discovered that pathogenic (toxigenic) strains. Moreover, later it was found that the gene for toxin production is located in the DNA of the B-type phage.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
22928352293263429hypothetical proteinBLASTP
229331622943411026Putative DNA-binding proteinQuickGO ontologyBLASTP
22944032294678276Putative nucleotide-binding proteinQuickGO ontologyBLASTP
229514822969681821Conserved putative secreted proteinQuickGO ontologyBLASTP
22970772297805729hypothetical proteinBLASTP
229779822988561059hypothetical proteinBLASTP
22989122299496585hypothetical proteinBLASTP
229948923010451557hypothetical proteinBLASTP
23014112302097687hypothetical proteinBLASTP
230209723047272631Putative helicaseQuickGO ontologyBLASTP
23047292305688960hypothetical proteinBLASTP
23056892306003315hypothetical proteinBLASTP
23078932308408516single-strand DNA-binding proteinQuickGO ontologyBLASTP
23084272308660234Putative DNA-binding proteinQuickGO ontologyBLASTP
23091272309804678hypothetical proteinBLASTP
23098792310220342hypothetical proteinBLASTP
23102102310485276hypothetical proteinBLASTP
23106012310759159hypothetical protein
23109482311757810potential surface-anchored proteinQuickGO ontologyBLASTP
231183023128761047Putative fimbrial associated sortase-like proteinQuickGO ontologyBLASTP
23128602313816957Putative fimbrial associated sortase-like proteinQuickGO ontologyBLASTP