Pre_GI Gene

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Host: NC_017066 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017066:262839 Rickettsia typhi str. TH1527 chromosome, complete genome

Host Lineage: Rickettsia typhi; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. R. prowazekii, and genomic comparisons demonstrate colinearity and similarity to the genome of that organism except for two independent inversions near the origin and terminus. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
2628392646081770multidrug ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
264785265054270hypothetical proteinBLASTP
2652192665621344cytochrome d ubiquinol oxidase subunit IQuickGO ontologyBLASTP
2666942677131020cytochrome d ubiquinol oxidase subunit IIQuickGO ontologyBLASTP
267973268851879glucosyltransferaseQuickGO ontologyBLASTP
2689902702281239proteaseQuickGO ontologyBLASTP
270350271060711phosphoribosylaminoimidazolesuccinocarboxamide synthaseQuickGO ontologyBLASTP
272020272256237hypothetical proteinBLASTP
2723792742861908threonyl-tRNA synthetaseQuickGO ontologyBLASTP
276549276956408hypothetical proteinBLASTP
2769492781451197hypothetical proteinBLASTP
2783752797391365outer membrane protein tolCQuickGO ontologyBLASTP
279741280154414hypothetical proteinBLASTP
2802872820471761hypothetical proteinBLASTP