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Query: NC_017066:262839:279741 Rickettsia typhi str. TH1527 chromosome, complete genome

Start: 279741, End: 280154, Length: 414

Host Lineage: Rickettsia typhi; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. R. prowazekii, and genomic comparisons demonstrate colinearity and similarity to the genome of that organism except for two independent inversions near the origin and terminus. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_006142:262825:279727279727280140414Rickettsia typhi str. Wilmington, complete genomehypothetical protein4e-70262
NC_017043:990395:102925810292581029656399Rickettsia montanensis str. OSU 85-930 chromosome, complete genomehypothetical protein3e-56216
NC_016930:293245:310149310149310547399Rickettsia philipii str. 364D chromosome, complete genomehypothetical protein2e-55214
NC_016915:278000:311560311560311958399Rickettsia rickettsii str. Hlp#2 chromosome, complete genomehypothetical protein5e-55212
NC_007940:266000:278998278998279381384Rickettsia bellii RML369-C, complete genomehypothetical protein7e-44175
NC_009883:1262000:127482412748241275207384Rickettsia bellii OSU 85-389, complete genomehypothetical protein7e-44175