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Query: NC_017066:262839:280287 Rickettsia typhi str. TH1527 chromosome, complete genome

Start: 280287, End: 282047, Length: 1761

Host Lineage: Rickettsia typhi; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. R. prowazekii, and genomic comparisons demonstrate colinearity and similarity to the genome of that organism except for two independent inversions near the origin and terminus. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_006142:262825:2802732802732820331761Rickettsia typhi str. Wilmington, complete genomerickettsial conserved hypothetical protein01043
NC_017043:990395:1029882102988210316241743Rickettsia montanensis str. OSU 85-930 chromosome, complete genomeankyrin3e-153542
NC_016930:293245:3107643107643124851722Rickettsia philipii str. 364D chromosome, complete genomehypothetical protein1e-144513
NC_016915:278000:3121753121753138961722Rickettsia rickettsii str. Hlp#2 chromosome, complete genomehypothetical protein3e-143509
NC_009883:1262000:1271356127135612733592004Rickettsia bellii OSU 85-389, complete genomeAnkyrin repeat7e-80298
NC_007940:266000:2756522756522775411890Rickettsia bellii RML369-C, complete genomeAnkyrin repeat1e-79297