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Query: NC_012207:831030:852884 Mycobacterium bovis BCG str. Tokyo 172, complete genome

Start: 852884, End: 853609, Length: 726

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Used for the production of BCG vaccine in Japan. Causative agent of classic bovine tuberculosis. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced. The pathology in cows is similar to the pathology of Mycobacterium tuberculosis in humans, with pulmonary TB leading to chronic debilitation, coughing, and further systemic spread to other organs. In addition, 1 to 2% of infected cows develop mycobacterial mastitis that results in shedding of the bacteria into the milk.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016768:830000:851943851943852668726Mycobacterium tuberculosis KZN 4207 chromosome, complete genomehypothetical protein4e-115414
NC_012943:830000:851939851939852664726Mycobacterium tuberculosis KZN 1435 chromosome, complete genomehypothetical protein4e-115414
NC_002945:831029:852931852931853656726Mycobacterium bovis AF2122/97, complete genomehypothetical protein4e-115414
NC_008595:661507:675903675903676619717Mycobacterium avium 104, complete genomehypothetical protein1e-83309
NC_010612:103081:1294871294871305781092Mycobacterium marinum M, complete genomehypothetical protein8e-48190
NC_020133:77341:908559085591619765Mycobacterium liflandii 128FXT, complete genomehypothetical protein1e-47189
NC_018581:3871000:388555238855523886520969Gordonia sp. KTR9 chromosome, complete genomehypothetical protein3e-23108