Some Help

Query: NC_008150:2599661:2615656 Yersinia pestis Antiqua, complete genome

Start: 2615656, End: 2616609, Length: 954

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Isolated from a soil sample from the Republic of Congo. Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia

SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017168:2560000:257702525770252577978954Yersinia pestis A1122 chromosome, complete genomeenhanced serine sensitivity protein SseB5e-173606
NC_017154:2901300:291729629172962918249954Yersinia pestis D106004 chromosome, complete genomehypothetical protein5e-173606
NC_010159:409500:450729450729451682954Yersinia pestis Angola, complete genomesseB protein5e-173606
NC_010634:3269010:329132532913253292278954Yersinia pseudotuberculosis PB1/+, complete genomeSseB family protein5e-173606
NC_009523:5475812:548285454828545483621768Roseiflexus sp. RS-1 chromosome, complete genomeSseB family protein3e-24112
NC_020541:1827689:183584618358461836580735Rhodanobacter sp. 2APBS1, complete genomeSseB protein4e-1065.5
NC_020541:1786500:180009818000981800841744Rhodanobacter sp. 2APBS1, complete genomeSseB protein9e-0961.2
NC_020541:4122852:413214641321464132880735Rhodanobacter sp. 2APBS1, complete genomeSseB protein9e-0857.8