Query: NC_011896:2660969 Mycobacterium leprae Br4923, complete genome
Start: 2660969, End: 2680099, Length: 19131
Host Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.
Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!
Subject Island | Start | End | Length | Subject Host Description | E-value | Bit score | Visual BLASTN | Visual BLASTP |
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NC_002677:2642860 | 2642860 | 2682483 | 39624 | Mycobacterium leprae TN, complete genome | 0 | 36620 | BLASTN svg | BLASTP svg |
NC_002677:1096500 | 1096500 | 1115169 | 18670 | Mycobacterium leprae TN, complete genome | 0 | 1154 | BLASTN svg | BLASTP svg |
NC_011896:1096500 | 1096500 | 1115212 | 18713 | Mycobacterium leprae Br4923, complete genome | 0 | 1146 | BLASTN svg | BLASTP svg |
NC_011896:563641 | 563641 | 583453 | 19813 | Mycobacterium leprae Br4923, complete genome | 0 | 1138 | BLASTN svg | BLASTP svg |
NC_002677:563500 | 563500 | 583444 | 19945 | Mycobacterium leprae TN, complete genome | 0 | 1138 | BLASTN svg | BLASTP svg |
NC_011896:34746* | 34746 | 57099 | 22354 | Mycobacterium leprae Br4923, complete genome | 0 | 1130 | BLASTN svg | BLASTP svg |
NC_002677:34750* | 34750 | 57099 | 22350 | Mycobacterium leprae TN, complete genome | 0 | 1130 | BLASTN svg | BLASTP svg |
NC_018581:759932 | 759932 | 801242 | 41311 | Gordonia sp. KTR9 chromosome, complete genome | 2e-47 | 198 | BLASTN svg | BLASTP svg |
NC_009142:515828* | 515828 | 535938 | 20111 | Saccharopolyspora erythraea NRRL 2338, complete genome | 3e-18 | 101 | BLASTN svg | BLASTP svg |
NC_014168:3013697* | 3013697 | 3036613 | 22917 | Segniliparus rotundus DSM 44985 chromosome, complete genome | 2e-12 | 81.8 | BLASTN svg | BLASTP svg |
NC_011004:5520771* | 5520771 | 5546781 | 26011 | Rhodopseudomonas palustris TIE-1, complete genome | 9e-09 | 69.9 | BLASTN svg | BLASTP svg |
NC_005296:5238882* | 5238882 | 5264891 | 26010 | Rhodopseudomonas palustris CGA009, complete genome | 9e-09 | 69.9 | BLASTN svg | BLASTP svg |
NC_015740:3486226 | 3486226 | 3509099 | 22874 | Pseudomonas stutzeri ATCC 17588 = LMG 11199 chromosome, complete | 4e-08 | 67.9 | BLASTN svg | BLASTP svg |
NC_015138:4666544 | 4666544 | 4688523 | 21980 | Acidovorax avenae subsp. avenae ATCC 19860 chromosome, complete | 1e-07 | 65.9 | BLASTN svg | BLASTP svg |
NC_008752:4665699 | 4665699 | 4688086 | 22388 | Acidovorax avenae subsp. citrulli AAC00-1, complete genome | 1e-07 | 65.9 | BLASTN svg | BLASTP svg |
NC_010804:2518695 | 2518695 | 2541488 | 22794 | Burkholderia multivorans ATCC 17616 chromosome 1, complete | 9e-06 | 60 | BLASTN svg | BLASTP svg |