Pre_GI: BLASTP Hits

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Query: NC_012581:519969:525357 Bacillus anthracis str. CDC 684 chromosome, complete genome

Start: 525357, End: 525686, Length: 330

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This organism was the first to be shown to cause disease by Dr. Robert Koch, leading to the formulation of Koch's postulates, which were verified by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. Anthrax is not transmitted due to person-to-person contact. The three forms of the disease reflect the sites of infection which include cutaneous (skin), pulmonary (lung), and intestinal. Pulmonary and intestinal infections are often fatal if left untreated. Spores are taken up by macrophages and become internalized into phagolysozomes (membranous compartment) whereupon germination initiates. Bacteria are released into the bloodstream once the infected macrophage lyses whereupon they rapidly multiply, spreading throughout the circulatory and lymphatic systems, a process that results in septic shock, respiratory distress and organ failure. The spores of this pathogen have been used as a terror weapon.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_011773:3729500:374758637475863747915330Bacillus cereus AH820 chromosome, complete genomehypothetical protein7e-44175
NC_014335:3645500:366355336635533663882330Bacillus cereus biovar anthracis str. CI chromosome, completeTraR/DksA family transcriptional regulator7e-44175
NC_005957:3716487:373499437349943735323330Bacillus thuringiensis serovar konkukian str. 97-27, completeconserved hypothetical protein, possible DnaK suppressor protein7e-44175
NC_012472:3743473:376082737608273761156330Bacillus cereus 03BB102, complete genomehypothetical protein7e-44175
NC_006274:3773335:379323637932363793565330Bacillus cereus E33L, complete genomeconserved hypothetical protein; possible DnaK suppressor protein2e-42171
NC_017200:3737185:375766737576673757996330Bacillus thuringiensis serovar finitimus YBT-020 chromosome,hypothetical protein1e-41167
NC_011725:3897450:391701339170133917342330Bacillus cereus B4264 chromosome, complete genomehypothetical protein3e-41166
NC_004722:3855326:387496138749613875290330Bacillus cereus ATCC 14579, complete genomeDnaK suppressor protein1e-40164
NC_011772:3863166:388308938830893883418330Bacillus cereus G9842, complete genomehypothetical protein1e-40164
NC_014171:3779956:379783337978333798162330Bacillus thuringiensis BMB171 chromosome, complete genomeDnaK suppressor protein1e-40164
NC_017208:3897253:391461539146153914944330Bacillus thuringiensis serovar chinensis CT-43 chromosome, completeDnaK suppressor protein1e-40164
NC_003909:3671468:369078636907863691100315Bacillus cereus ATCC 10987, complete genomehypothetical protein3e-38157
NC_010184:3757000:377287837728783773207330Bacillus weihenstephanensis KBAB4, complete genometranscriptional regulator, TraR/DksA family1e-37154
NC_007530:3694940:371292737129273713241315Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein5e-36149
NC_011969:3627980:364533336453333645620288Bacillus cereus Q1 chromosome, complete genomehypothetical protein5e-34142
NC_009674:2624817:264389326438932644222330Bacillus cytotoxicus NVH 391-98 chromosome, complete genomeTraR/DksA family transcriptional regulator3e-31133
NC_017138:980696:983632983632983919288Bacillus megaterium WSH-002 chromosome, complete genometranscriptional regulator TraR/DksA3e-0753.9
NC_014019:4094750:410983841098384110125288Bacillus megaterium QM B1551 chromosome, complete genomehypothetical protein3e-0753.9
NC_009848:1494253:149717914971791497553375Bacillus pumilus SAFR-032, complete genomehypothetical protein5e-0753.1