Pre_GI Gene

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Host: NC_012472 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012472:3743473 Bacillus cereus 03BB102, complete genome

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: Bacillus cereus 03BB102 was cultured from the blood of a 39 year old San Antonio, Texas welder who died as a result of a severe pneumonia thought to be caused by this microbe. Unlike B. anthracis, the isolate is hemolytic, motile and resistant to gamma phage. However, it is positive for a DFA-based cell wall test for B. anthracis, and it has all or most of the pXO1 pathogenicity island sequences including the sequences for pag, cya and lef. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
37434733743997525hypothetical proteinBLASTP
37440293744397369hypothetical proteinBLASTP
37444133744778366hypothetical proteinBLASTP
374494537463301386hypothetical proteinBLASTP
37464973746751255hypothetical proteinBLASTP
37467743747451678hydrolase haloacid dehalogenase-like familyQuickGO ontologyBLASTP
37474943748126633orotate phosphoribosyltransferaseQuickGO ontologyBLASTP
37481233748839717orotidine 5-phosphate decarboxylaseQuickGO ontologyBLASTP
37488243749753930dihydroorotate oxidaseQuickGO ontologyBLASTP
37497503750529780dihydroorotate dehydrogenase electron transfer subunitQuickGO ontologyBLASTP
375052637537443219carbamoyl-phosphate synthase large subunitQuickGO ontologyBLASTP
375372937548261098carbamoyl-phosphate synthase small subunitQuickGO ontologyBLASTP
375482337561091287dihydroorotaseQuickGO ontologyBLASTP
37560933757007915aspartate carbamoyltransferaseQuickGO ontologyBLASTP
375715637584391284uracil permeaseQuickGO ontologyBLASTP
37585863759128543pyrimidine operon regulatory proteinQuickGO ontologyBLASTP
37593313760239909ribosomal large subunit pseudouridine synthase RluA familyQuickGO ontologyBLASTP
37602443760702459signal peptidase IIQuickGO ontologyBLASTP
37608273761156330hypothetical proteinBLASTP