Pre_GI Gene

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Host: NC_014335 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_014335:3645500 Bacillus cereus biovar anthracis str. CI chromosome, complete

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain probably caused lethal anthrax in chimpanzee Leo in the rainforest of the Tai National Park, Cote d'Ivoire. It belongs to a collection of genetically closely related bacteria, isolated in 2001 and 2002 from deceased wild chimpanzees living in this rain forest area. An autopsy showed symptoms typical of anthrax, but the bacterium isolated was motile, unlike B.anthracis. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
364566936467391071proline dipeptidaseQuickGO ontologyBLASTP
36468243647348525hypothetical proteinBLASTP
36473803647748369hypothetical proteinBLASTP
36477643648195432hypothetical proteinBLASTP
364829636496811386putative transporter proteinQuickGO ontologyBLASTP
36498483650102255hypothetical proteinBLASTP
36502203650852633orotate phosphoribosyltransferaseQuickGO ontologyBLASTP
36508493651565717orotidine 5-phosphate decarboxylaseQuickGO ontologyBLASTP
36515503652479930dihydroorotate dehydrogenaseQuickGO ontologyBLASTP
36524763653255780dihydroorotate dehydrogenase electron transfer subunitQuickGO ontologyBLASTP
365325236563083057carbamoyl-phosphate synthase large subunitQuickGO ontologyBLASTP
365645536575521098carbamoyl-phosphate synthase small subunitQuickGO ontologyBLASTP
365754936588351287dihydroorotaseQuickGO ontologyBLASTP
36588193659733915aspartate carbamoyltransferase catalytic subunitQuickGO ontologyBLASTP
365988236611651284uracil-xanthine permeaseQuickGO ontologyBLASTP
36613123661854543uracil phosphoribosyltransferaseQuickGO ontologyBLASTP
36620573662965909ribosomal large subunit pseudouridylate synthase DQuickGO ontologyBLASTP
36629703663428459lipoprotein signal peptidaseQuickGO ontologyBLASTP
36635533663882330TraRDksA family transcriptional regulatorQuickGO ontologyBLASTP
366403836668032766isoleucyl-tRNA synthetaseQuickGO ontologyBLASTP
36671513667657507DivIVA family proteinQuickGO ontologyBLASTP
36677473668514768RNA-binding S4 domain-containing proteinQuickGO ontologyBLASTP
36685303668793264membrane proteinQuickGO ontologyBLASTP
36688003669267468hypothetical proteinBLASTP
36692873669961675hypothetical proteinBLASTP
36699583670815858hypothetical proteinBLASTP