Pre_GI: BLASTP Hits

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Query: NC_004557:2289135:2301843 Clostridium tetani E88, complete genome

Start: 2301843, End: 2303219, Length: 1377

Host Lineage: Clostridium tetani; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a virulent nonsporulating variant of strain Massachusetts used in vaccine production. Causes tetanus. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism causes tetanus (lockjaw) in humans. At the tissue level, the bacterium then releases an exotoxin called tetanospasmin that causes certain nervous system irregularities by means of retrograde tramsmission through neurons to the brain. If nervous impulses cannot be checked by normal inhibitory mechanisms, it produces the generalized muscular spasms characteristic of tetanus.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_008261:1048515:1056901105690110582681368Clostridium perfringens ATCC 13124, complete genomeethanolamine ammonia-lyase, large subunit0771
NC_003366:1091766:1100143110014311015101368Clostridium perfringens str. 13, complete genomeethanolamine ammonia lyase heavy chain0771
NC_017179:2067015:2075183207518320765471365Clostridium difficile BI1, complete genomeethanolamine ammonia lyase large subunit0764
NC_013315:2059007:2067175206717520685391365Clostridium difficile CD196 chromosome, complete genomeethanolamine/propanediol ammonia-lyase heavy chain0764
NC_015275:4493500:4502531450253145038951365Clostridium lentocellum DSM 5427 chromosome, complete genomeEthanolamine ammonia-lyase0749
NC_013517:1055854:1134833113483311361971365Sebaldella termitidis ATCC 33386, complete genomeEthanolamine ammonia-lyase0739
NC_013192:63111:7131071310726741365Leptotrichia buccalis DSM 1135, complete genomeEthanolamine ammonia lyase large subunit0729
NC_014614:284005:2937182937182950851368Clostridium sticklandii, complete genomeethanolamine ammonia-lyase, large subunit, heavy chain0727
NC_014654:2277461:2290600229060022919641365Halanaerobium sp. 'sapolanicus' chromosome, complete genomeEthanolamine ammonia-lyase0716
NC_009633:286677:2948512948512962181368Alkaliphilus metalliredigens QYMF chromosome, complete genomeethanolamine ammonia lyase large subunit0711
NC_009922:868262:8740228740228753891368Alkaliphilus oremlandii OhILAs, complete genomeEthanolamine ammonia lyase large subunit0709
NC_014376:1586649:1595769159576915971481380Clostridium saccharolyticum WM1 chromosome, complete genomeEthanolamine ammonia-lyase0701
NC_009253:1381401:1386640138664013880251386Desulfotomaculum reducens MI-1 chromosome, complete genomeethanolamine ammonia lyase large subunit0674
NC_020291:795500:7955557955557969221368Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomeethanolamine ammonia-lyase heavy chain0653
NC_012491:5914500:5930544593054459319051362Brevibacillus brevis NBRC 100599, complete genomeprobable ethanolamine ammonia-lyase heavy chain0639
NC_016584:1998000:2023882202388220252461365Desulfosporosinus orientis DSM 765 chromosome, complete genomeethanolamine ammonia-lyase, large subunit0635
NC_014019:3543389:3555800355580035571641365Bacillus megaterium QM B1551 chromosome, complete genomeethanolamine ammonia-lyase, large subunit4e-177621
NC_018870:705900:7235747235747249651392Thermacetogenium phaeum DSM 12270 chromosome, complete genomeethanolamine ammonia-lyase heavy chain1e-176619
NC_010468:1343228:1357697135769713590581362Escherichia coli ATCC 8739, complete genomeEthanolamine ammonia lyase large subunit6e-173607
NC_016584:1714507:1726633172663317279971365Desulfosporosinus orientis DSM 765 chromosome, complete genomeethanolamine ammonia-lyase, large subunit2e-171602
NC_018515:1663912:1680789168078916821531365Desulfosporosinus meridiei DSM 13257 chromosome, complete genomeethanolamine ammonia-lyase, large subunit1e-169596
NC_014654:2277461:2289202228920222905841383Halanaerobium sp. 'sapolanicus' chromosome, complete genomeEthanolamine ammonia-lyase2e-164578
NC_007651:3719191:3737347373734737387441398Burkholderia thailandensis E264 chromosome I, complete sequenceethanolamine ammonia-lyase, large subunit5e-141501
NC_020409:512861:5254235254235269131491Desulfovibrio piezophilus str. nov C1TLV30 chromosome, completeEthanolamine ammonia-lyase heavy chain1e-134480
NC_017986:3283433:3300508330050833019021395Pseudomonas putida ND6 chromosome, complete genomeethanolamine ammonia lyase large subunit3e-133475
NC_009937:4090404:4090404409040440917921389Azorhizobium caulinodans ORS 571, complete genomeethanolamine ammonia-lyase large subunit8e-133474
NC_004129:6240904:6245923624592362473171395Pseudomonas fluorescens Pf-5, complete genomeethanolamine ammonia-lyase, large subunit3e-132471
NC_008825:2564965:2581884258188425832931410Methylibium petroleiphilum PM1, complete genomeputative ethanolamine ammonia-lyase heavy chain protein1e-131470
NC_014734:183214:1868081868081881931386Paludibacter propionicigenes WB4 chromosome, complete genomeethanolamine ammonia-lyase heavy chain9e-130463
NC_016830:5994494:5996067599606759974611395Pseudomonas fluorescens F113 chromosome, complete genomeEutB protein2e-129462
NC_015379:6023926:6025626602562660270201395Pseudomonas brassicacearum subsp. brassicacearum NFM421 chromosome,ethanolamine ammonia-lyase, heavy chain3e-129462
NC_004129:6240904:6243676624367662458712196Pseudomonas fluorescens Pf-5, complete genomeethanolamine ammonia-lyase1e-83310