Pre_GI Island

Some Help

n1_4mer:GRV/n1_4mer:RV = (Global Relative Variance of OU patterns) / (Local Relative Variance of OU patterns)

n0_4mer:D = Distance between local and global OU patterns

n0_4mer:PS = Distance between 2 strands of same DNA molecule

Selected loci indicated by large D, increased GRV associated with decreased RV and moderate increase in PS

NC_011244: Borrelia recurrentis A1, complete genome

NCBI: NC_011244

Host Lineage: Borrelia recurrentis; Borrelia; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria

General Information: Borrelia recurrentis isolated from adult patient with louse-borne relapsing fever in Ethiopia. Borrelia recurrentis is the causative agent of louse-borne relapsing fever. Prior to World War II, this organism was responsible for large disease outbreaks with a mortality of up to 40% in much of the world. Currently this disease is limited to parts of Africa, China, and Peru. B. recurrentis is transmitted when infected human body lice (Pediculus humanus) are crushed and their fluids contaminate mucous membranes or breaks in the skin. Relapsing fever is characterized by a period of chills, fever, headache, and malaise, an asymptomatic period, followed by another episode of symptoms. This cycle of relapsing is due to changes in the surface proteins of Borrelia, which allow it to avoid detection and removal by the host immune system. This antigenic variation is the result of homologous recombination of silent proteins into an expressed locus, causing partial or complete replacement of one serotype with another.

Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

#StartEndLengthIsland TextGRV_RVDPSNeighboursClusterSub ClusterBLASTNKey Word ConfirmationOther DB ConfirmationDownload Island
11*2432124321Island text2.3265520.789236.3214Neighbours21BLASTNIslandViewer 1.gbk
294756*13088636131Island text1.8381517.03733.1648Neighbours21BLASTN94756.gbk
3213853*23570621854Island text4.9586517.869238.8259Neighbours21BLASTN+IslandViewer 213853.gbk
431937333914219770Island text1.969617.570536.8782Neighbours21BLASTN319373.gbk
5412500*43220819709Island text2.0313316.941329.9306Neighbours21BLASTN412500.gbk
6497212*52075023539Island text2.1257116.150932.4278Neighbours21BLASTN+497212.gbk
7746801*76961422814Island text2.3347517.42836.7897Neighbours21BLASTN746801.gbk
8863306*88429320988Island text2.0305417.589536.0823Neighbours21BLASTN863306.gbk