Pre_GI Gene

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Host: NC_011244 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011244:863306 Borrelia recurrentis A1, complete genome

Host Lineage: Borrelia recurrentis; Borrelia; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria

General Information: Borrelia recurrentis isolated from adult patient with louse-borne relapsing fever in Ethiopia. Borrelia recurrentis is the causative agent of louse-borne relapsing fever. Prior to World War II, this organism was responsible for large disease outbreaks with a mortality of up to 40% in much of the world. Currently this disease is limited to parts of Africa, China, and Peru. B. recurrentis is transmitted when infected human body lice (Pediculus humanus) are crushed and their fluids contaminate mucous membranes or breaks in the skin. Relapsing fever is characterized by a period of chills, fever, headache, and malaise, an asymptomatic period, followed by another episode of symptoms. This cycle of relapsing is due to changes in the surface proteins of Borrelia, which allow it to avoid detection and removal by the host immune system. This antigenic variation is the result of homologous recombination of silent proteins into an expressed locus, causing partial or complete replacement of one serotype with another.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
8633068658942589DNA mismatch repair protein MutSQuickGO ontologyBLASTP
866626867057432hypothetical proteinBLASTP
8670328685161485transcription elongation factor NusAQuickGO ontologyBLASTP
8684978711362640translation initiation factor IF-2QuickGO ontologyBLASTP
871126871515390ribosome-binding factor AQuickGO ontologyBLASTP
871525872370846tRNA pseudouridine 55 synthaseQuickGO ontologyBLASTP
87259287293334230S ribosomal protein S15QuickGO ontologyBLASTP
8729478751002154polynucleotide phosphorylasepolyadenylaseQuickGO ontologyBLASTP
8751108766211512hypothetical proteinBLASTP
8765968778851290hypothetical proteinBLASTP
8777418789491209hypothetical proteinBLASTP
8789678800941128queuine tRNA-ribosyltransferaseQuickGO ontologyBLASTP
8800878816101524virulence factor MviN proteinQuickGO ontologyBLASTP
8816078830371431hypothetical proteinBLASTP
8830318842931263pantothenate metabolism flavoproteinQuickGO ontologyBLASTP