Pre_GI Gene

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Host: NC_017516 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017516:2220000 Neisseria meningitidis H44/76 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
222038722214121026peptide chain release factor 2QuickGO ontologyBLASTP
22215932222495903phospholipase patatin familyQuickGO ontologyBLASTP
22228302223279450DoxX family proteinQuickGO ontologyBLASTP
22233522223660309hypothetical protein
22237762224618843hypothetical proteinBLASTP
22246082225354747hypothetical proteinBLASTP
22253762225963588igma-70 family RNA polymerase sigma factorQuickGO ontologyBLASTP
22264072226829423putative lipoproteinQuickGO ontologyBLASTP
22273032228268966transposase IS30 familyQuickGO ontologyBLASTP
22290022229604603protein RimNQuickGO ontologyBLASTP
222963822309091272phosphoribosylamine--glycine ligaseQuickGO ontologyBLASTP
22310672231384318hypothetical proteinBLASTP
22314362232047612hypothetical proteinBLASTP
22321102233045936electron transfer flavoprotein subunit alphaQuickGO ontologyBLASTP
22330562233805750electron transfer flavoprotein subunit betaQuickGO ontologyBLASTP
22340322235000969lipopolysaccharide heptosyltransferase IQuickGO ontologyBLASTP
22350372235672636isochorismatase family proteinQuickGO ontologyBLASTP
22357862236466681hypothetical proteinBLASTP
223672422377281005glyceraldehyde-3-phosphate dehydrogenase type IQuickGO ontologyBLASTP
223817222407662595DNA mismatch repair protein MutSQuickGO ontologyBLASTP