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Query: NC_006570:141966:163417 Francisella tularensis subsp. tularensis Schu 4, complete genome

Start: 163417, End: 163653, Length: 237

Host Lineage: Francisella tularensis; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria

General Information: This subspecies is virulent in humans, and the strain is a clinical isolate that is also virulent in an animal model. Originally isolated from a human case of tularemia in 1951. There are a large number of insertion sequences including a mariner element, which is a transposon typically found in eukaryotes and is the first instance of this element to be found in a microbe, which may have acquired it during transit through one of the insect vectors. Causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016937:141984:163435163435163671237Francisella tularensis subsp. tularensis TI0902 chromosome,hypothetical protein2e-22103
NC_008601:1658454:166321016632101663446237Francisella tularensis subsp. novicida U112, complete genomehypothetical membrane protein2e-22103
NC_010677:214712:236036236036236272237Francisella tularensis subsp. mediasiatica FSC147, complete genomehypothetical membrane protein2e-22103
NC_008245:141982:163433163433163669237Francisella tularensis subsp. tularensis FSC 198, complete genomehypothetical membrane protein2e-22103
NC_009257:226417:247868247868248104237Francisella tularensis subsp. tularensis WY96-3418 chromosome,hypothetical protein2e-22103
NC_016933:141984:163435163435163671237Francisella tularensis TIGB03 chromosome, complete genomehypothetical protein2e-22103
NC_008369:1667437:167219216721921672428237Francisella tularensis subsp. holarctica OSU18, complete genomehypothetical protein2e-21101
NC_009749:1663500:166844416684441668680237Francisella tularensis subsp. holarctica FTA, complete genomehypothetical membrane protein2e-21101
NC_007880:1667922:167267816726781672914237Francisella tularensis subsp. holarctica, complete genomehypothetical membrane protein2e-21101
NC_010336:1117325:113892011389201139174255Francisella philomiragia subsp. philomiragia ATCC 25017, completehypothetical protein8e-1785.5