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Query: NC_004917:241053:249168 Helicobacter hepaticus ATCC 51449, complete genome

Start: 249168, End: 253067, Length: 3900

Host Lineage: Helicobacter hepaticus; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: This organism was found to be linked to an increasing incidence of liver tumors in mouse colonies at the National Cancer Institute in 1992. Normally it resides in the lower intestines, but it can cause chronic hepatitis. This organism has a similar urease gene cluster and cytolethal distending toxin as compared to Helicobacter pylori, but lacks other virulence factors such as the vacuolating cytotoxin and the cag pathogenicity island. However, it does contain a pathogenicity island that encodes proteins similar to those found in a type IV secretion system. Causes liver disease. This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). This species was associated with an increase in liver tumors. It can cause active chronic hepatitis and typhlitis (inflammation of a region at the beginning of the large intestine), hepatocellular tumors, and gastric bowel disease in various mice strains.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_004917:366104:3735143735143745211008Helicobacter hepaticus ATCC 51449, complete genomehypothetical protein4e-46187
NC_009802:114749:131449131449132273825Campylobacter concisus 13826, complete genomehypothetical protein1e-25119
NC_009802:114749:1240871240871278543768Campylobacter concisus 13826, complete genomehypothetical protein2e-25118
NC_009802:114749:129238129238130068831Campylobacter concisus 13826, complete genome3-deoxy-D-arabino-heptulosonate 7-phosphate synthase5e-25117