Pre_GI: BLASTP Hits

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Query: NC_009142:2822260:2840045 Saccharopolyspora erythraea NRRL 2338, complete genome

Start: 2840045, End: 2841007, Length: 963

Host Lineage: Saccharopolyspora erythraea; Saccharopolyspora; Pseudonocardiaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Source of the antibiotic erythromycin. Saccharopolyspora erythraea is the soil bacterium that produces the industrially important antibiotic erythromycin A. Erythromycin is a clinically important and potent macrolide antibiotic. It is used to treat infections caused by several prokaryotic pathogens such as Streptococcus, Staphylococcus, Mycoplasma, Ureaplasma, Chlamydia and Legionella. Production of this antibiotic is lower than others in the same class, such as penicillin or cephalosporin, which has led to the development of a genetic system to attempt to enhance the production of erythromycin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_015711:6796082:68133466813346682547712132Myxococcus fulvus HW-1 chromosome, complete genomenon-ribosomal peptide synthetase3e-1789.4
NC_013892:1890500:18981991898199192251024312Xenorhabdus bovienii SS-2004 chromosome, complete genomephenylalanine racemase3e-1582.8
NC_008095:4858117:48754704875470488905613587Myxococcus xanthus DK 1622, complete genomenon-ribosomal peptide synthetase8e-1581.3
NC_012962:3060063:30666173066617307897612360Photorhabdus asymbiotica, complete genomecomplete genome; segment 7/173e-1479.3
NC_020126:4974877:49748774974877499294218066Myxococcus stipitatus DSM 14675, complete genomenon-ribosomal peptide synthetase5e-1479
NC_005126:2222000:22265162226516223899812483Photorhabdus luminescens subsp. laumondii TTO1, complete genomehypothetical protein6e-1478.6
NC_014500:1862000:1883742188374218918298088Dickeya dadantii 3937 chromosome, complete genomeNonribosomal peptide synthetase8e-1478.2
NC_020126:3383902:33920463392046341467722632Myxococcus stipitatus DSM 14675, complete genomenon-ribosomal peptide synthetase4e-1375.5
NC_015711:6522808:65228086522808654153618729Myxococcus fulvus HW-1 chromosome, complete genomenon-ribosomal peptide synthetase/polyketide synthase8e-1271.2
NC_015711:6266432:6302595630259563077875193Myxococcus fulvus HW-1 chromosome, complete genomenon-ribosomal peptide synthetase2e-1170.5
NC_011884:2817054:2830686283068628380747389Cyanothece sp. PCC 7425, complete genomeBeta-ketoacyl synthase2e-1170.1
NC_009085:131000:1375981375981414433846Acinetobacter baumannii ATCC 17978, complete genomeAmino acid adenylation4e-1168.9
NC_014623:9552:2685426854315994746Stigmatella aurantiaca DW4/3-1 chromosome, complete genometubf protein5e-1168.9
NC_017162:158289:1646221646221685813960Acinetobacter baumannii 1656-2 chromosome, complete genomeAmino acid adenylation7e-1168.2
NC_010611:154307:1608311608311647903960Acinetobacter baumannii ACICU, complete genomeNon-ribosomal peptide synthetase protein1e-1067.4
NC_011595:3607402:3615024361502436189833960Acinetobacter baumannii AB307-0294, complete genomeTyrocidine synthetase 31e-1067
NC_011586:164746:1712291712291751883960Acinetobacter baumannii AB0057 chromosome, complete genomeamino acid adenylation1e-1067
NC_010410:3777076:3784698378469837886573960Acinetobacter baumannii AYE, complete genomeputative Non-ribosomal peptide synthetase1e-1067
NC_014228:1929665:19314471931447194943117985Xenorhabdus nematophila ATCC 19061, complete genomeNon-ribosomal peptide synthetase2e-1066.6
NC_007005:4411388:44113884411388443141820031Pseudomonas syringae pv. syringae B728a, complete genomeAmino acid adenylation2e-1066.6
NC_017030:3091313:31290853129085314133312249Corallococcus coralloides DSM 2259 chromosome, complete genomenon-ribosomal peptide synthetase3e-1066.2
NC_017387:147906:1543831543831583423960Acinetobacter baumannii TCDC-AB0715 chromosome, complete genomenon-ribosomal peptide synthetase protein6e-1065.1
NC_017171:155836:1623131623131662723960Acinetobacter baumannii MDR-ZJ06 chromosome, complete genomenon-ribosomal peptide synthetase protein6e-1065.1
NC_017082:5789534:5818939581893958254156477Bradyrhizobium sp. S23321, complete genomepolyketide/non-ribosomal peptide synthetase8e-1064.7
NC_014722:1971305:19819841981984199935917376Burkholderia rhizoxinica HKI 454, complete genomeNon-ribosomal peptide synthetase modules1e-0964.3
NC_014718:102852:1143111143111226328322Burkholderia rhizoxinica HKI 454 chromosome, complete genomeNon-ribosomal peptide synthetase modules1e-0964.3
NC_016603:3259432:3266015326601532699743960Acinetobacter calcoaceticus PHEA-2 chromosome, complete genomenon-ribosomal peptide synthetase, terminal component1e-0963.9
NC_014722:1552454:1576869157686915847197851Burkholderia rhizoxinica HKI 454, complete genomeRhiF2e-0963.5
NC_020126:6791726:68156136815613682728511673Myxococcus stipitatus DSM 14675, complete genome3-oxoacyl-ACP reductase2e-0963.2
NC_014718:440960:4463234463234539367614Burkholderia rhizoxinica HKI 454 chromosome, complete genomeNon-ribosomal peptide synthetase modules3e-0962.8
NC_005126:1265071:1293627129362712990025376Photorhabdus luminescens subsp. laumondii TTO1, complete genome4e-0962.8
NC_014259:3984568:3992186399218639961453960Acinetobacter sp. DR1 chromosome, complete genomenon-ribosomal peptide synthetase protein4e-0962.4
NC_020126:3383902:3414674341467434213876714Myxococcus stipitatus DSM 14675, complete genomenon-ribosomal peptide synthetase8e-0961.6
NC_012962:1661683:1666017166601716759499933Photorhabdus asymbiotica, complete genomesimilar to different toxins like syringomycin synthetase and gramicidin s synthase 29e-0961.2
NC_004547:1683593:16835931683593170473921147Erwinia carotovora subsp. atroseptica SCRI1043, complete genomenon-ribosomal peptide synthetase1e-0860.8
NC_013722:1785692:17995971799597181656416968Xanthomonas albilineans, complete genomeprobable non-ribosomal peptide synthetase protein2e-0860.5
NC_013722:1816561:17995971799597181656416968Xanthomonas albilineans, complete genomeprobable non-ribosomal peptide synthetase protein2e-0860.5
NC_020291:397696:4128934128934207917899Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomepolyketide synthase PksM2e-0860.5
NC_020126:4517133:45171334517133454241325281Myxococcus stipitatus DSM 14675, complete genomenon-ribosomal peptide synthetase2e-0860.5
NC_007435:1981164:2006482200648220095233042Burkholderia pseudomallei 1710b chromosome II, complete sequenceputative peptide synthase protein2e-0860.1
NC_006351:142788:1681571681571709642808Burkholderia pseudomallei K96243 chromosome 2, complete sequencepeptide synthase protein2e-0860.1
NC_009078:142794:1678061678061709643159Burkholderia pseudomallei 1106a chromosome II, complete sequenceputative non-ribosomal peptide synthase3e-0859.7
NC_012962:1661683:16975321697532171390516374Photorhabdus asymbiotica, complete genomesyringopeptin synthetase b3e-0859.3
NC_018750:8210500:8211951821195182162644314Streptomyces venezuelae ATCC 10712, complete genomehypothetical protein4e-0859.3
NC_014718:630188:6419046419046461274224Burkholderia rhizoxinica HKI 454 chromosome, complete genomeNon-ribosomal peptide synthetase modules5e-0858.9
NC_012962:3499900:35110903511090353149220403Photorhabdus asymbiotica, complete genomeSimilar to proteins involved in antibiotic biosynthesis6e-0858.5
NC_011725:2365647:23721142372114238699614883Bacillus cereus B4264 chromosome, complete genomebacitracin synthetase 16e-0858.5
NC_010162:9502480:95024809502480951351611037Sorangium cellulosum 'So ce 56', complete genomeNRPS/PKS hybrid8e-0858.2
NC_012522:5952307:59688875968887597971010824Rhodococcus opacus B4, complete genomeputative non-ribosomal peptide synthetase8e-0858.2
NC_008095:4189082:42203944220394423409713704Myxococcus xanthus DK 1622, complete genomenon-ribosomal peptide synthetase1e-0757.8
NC_017082:6444522:6486937648693764908423906Bradyrhizobium sp. S23321, complete genomehypothetical protein1e-0757.8
NC_012880:1765920:1765920176592017744608541Dickeya dadantii Ech703, complete genomeamino acid adenylation domain protein1e-0757.8
NC_011772:2305000:23180482318048233293014883Bacillus cereus G9842, complete genomebacitracin synthetase 12e-0757.4
NC_015859:3177199:3177199317719931833816183Corynebacterium variabile DSM 44702 chromosome, complete genomenonribosomal peptide synthetase2e-0757
NC_015968:1165829:1179686117968611835463861Enterobacter asburiae LF7a chromosome, complete genomeamino acid adenylation domain-containing protein2e-0756.6
NC_007777:2841000:28668692866869288033813470Frankia sp. CcI3, complete genomeAmino acid adenylation2e-0756.6
NC_011726:1911500:1929047192904719334594413Cyanothece sp. PCC 8801, complete genomeamino acid adenylation domain protein2e-0756.6
NC_013161:1878700:1898874189887419032864413Cyanothece sp. PCC 8802, complete genomeamino acid adenylation domain protein2e-0756.6
NC_017208:2432027:24384942438494245337314880Bacillus thuringiensis serovar chinensis CT-43 chromosome, completepeptide synthetase2e-0756.6
NC_013892:2108175:21154932115493212622910737Xenorhabdus bovienii SS-2004 chromosome, complete genomepeptide synthetase XpsB3e-0756.2
NC_014171:2350679:23571462357146237202814883Bacillus thuringiensis BMB171 chromosome, complete genomepeptide synthetase3e-0756.2
NC_016584:3826300:3829172382917238363207149Desulfosporosinus orientis DSM 765 chromosome, complete genomeamino acid adenylation enzyme/thioester reductase family protein3e-0756.2
NC_004722:2399374:24104512410451242072510275Bacillus cereus ATCC 14579, complete genomePeptide synthetase3e-0756.2
NC_020453:1072979:10842381084238112047136234Agromonas oligotrophica S58 DNA, complete genomecyclic nucleotide binding protein4e-0755.8
NC_020453:1084238:10842381084238112047136234Agromonas oligotrophica S58 DNA, complete genomecyclic nucleotide binding protein4e-0755.8
NC_008260:2021162:2031340203134020354254086Alcanivorax borkumensis SK2, complete genomenon-ribosomal peptide synthase fragment4e-0755.8
NC_012962:3568046:36049733604973362047615504Photorhabdus asymbiotica, complete genomesimilar to Syringopeptin synthetase C5e-0755.5
NC_020126:6344827:6363701636370163689205220Myxococcus stipitatus DSM 14675, complete genomenon-ribosomal peptide synthetase5e-0755.5
NC_015564:484994:48499448499450182616833Amycolicicoccus subflavus DQS3-9A1 chromosome, complete genomeExopolyphosphatase6e-0755.1
NC_015376:2241000:2256381225638122605834203Burkholderia gladioli BSR3 chromosome chromosome 2, completePutative indigoidine synthase IndC1e-0654.7
NC_003155:3913789:393361339336133934425813Streptomyces avermitilis MA-4680, complete genomenon-ribosomal peptide synthetase1e-0654.3
NC_007645:3934239:3953985395398539625468562Hahella chejuensis KCTC 2396, complete genomeNon-ribosomal peptide synthetase modules and related protein2e-0653.9
NC_007651:2639553:2658514265851426607452232Burkholderia thailandensis E264 chromosome I, complete sequencenonribosomal peptide synthetase, putative2e-0653.9
NC_010180:213825:22019222019223509814907Bacillus weihenstephanensis KBAB4 plasmid pBWB401, completeamino acid adenylation domain2e-0653.5
NC_012522:2031786:20357042035704204715411451Rhodococcus opacus B4, complete genomeputative non-ribosomal peptide synthetase3e-0653.1
NC_013665:231023:2310232310232350304008Methanocella paludicola SANAE, complete genomeputative peptide synthetase3e-0652.8
NC_012214:1267589:12777741277774129886021087Erwinia pyrifoliae Ep1/96, complete genomeNon-ribosomal peptide synthetase, similar to N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase3e-0652.8
NC_012880:3529017:3556672355667235606043933Dickeya dadantii Ech703, complete genomeamino acid adenylation domain protein4e-0652.4
NC_003919:2435058:2449906244990624559326027Xanthomonas axonopodis pv. citri str. 306, complete genomeATP-dependent serine activating enzyme4e-0652.4
NC_016906:1268606:12931731293173130936616194Gordonia polyisoprenivorans VH2 chromosome, complete genomeputative non-ribosomal peptide synthetase7e-0651.6
NC_008268:2313583:23169792316979232851911541Rhodococcus sp. RHA1, complete genomenon-ribosomal peptide synthetase8e-0651.6
NC_010125:2884762:29123572912357292571813362Gluconacetobacter diazotrophicus PAl 5, complete genomeputative nonribosomal peptide synthetases (NPRS)8e-0651.6